The Correlation Characteristics Between Mental Health and Gut Microbiota of College Students in Qingyuan Vocational Education City

NCT06595095 | Not Yet Recruiting

• 1 other identifier: zhujiangjy-20240701
• Study Type: observational
• Target: 600
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn about the mental health status and gut microbiota characteristics of college students in Qingyuan Vocational Education City. The main question it aims to answer is: How is the mental condition of college students in Qingyuan Vocational Education City? Is there a correlation between the mental condition and the microbial characteristics of college students in Qingyuan Vocational Education City? Participants will answer online survey questions about their demographic characteristics, disease history, gastrointestinal status, lifestyle habits, and psychological health information. 200 participants from each of the following groups will be included: healthy individuals, anxious Individuals and depressive Individuals. Fecal samples will be collected for microbiome testing and analysis to obtain their microbial characteristics and to analyze the impact of mental health status on microbial changes.

Conditions

Depression; Anxiety

Outcome Measures

Primary Outcomes (1)

• Microbiota Characteristic Data

  The characteristics of microbiota include composition, abundance, and diversity, etc.

  2024.10-2025.9

Secondary Outcomes (4)

• general information of participants by questionnaire

  2024.10-2025.9

• Self-Rating Anxiety Scale SAS

  2024.10-2025.9

• Self-rating depression scale SDS

  2024.10-2025.9

• Pittsburgh sleep quality index PSQI

  2024.10-2025.9

Study Arms (3)

Healthy individuals

Anxious Individuals

Depressive Individuals

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

College students aged 18-25 years old at Qingyuan Vocational Education City

You may qualify if:

• Healthy Individuals:
• Ages 18 to 25 years old.
• Resident in the local area for more than one month.
• No obvious signs or symptoms of disease.
• Good psychological condition.
• College students currently enrolled in Qingyuan Vocational Education City.
• Having signed an informed consent form, willing to provide relevant survey information and fecal samples.
• Anxious Individuals:
• Ages 18 to 25 years old.
• Resident in the local area for more than one month.
• Self-rating anxiety scale score greater than or equal to 50.
• College students currently enrolled in Qingyuan Vocational Education City.
• Having signed an informed consent form, willing to provide relevant survey information and fecal samples.
• Depressive Individuals:
• Ages 18 to 25 years old.

You may not qualify if:

• Pregnant and Lactating Women.

Sponsors & Collaborators

• Zhujiang Hospital: lead

Study Sites (1)

Zhujiang hospital of southern medical university

Guangzhou, Guangdong, 510280, China

Location

MeSH Terms

Conditions

Depression; Anxiety Disorders

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Mental Disorders

Study Officials

• Yan He, Doctor

  Southern Medical University, China

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Yumei Liu, Master

CONTACT

18810795365; liuyumei1007@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 10, 2024
• First Posted: September 19, 2024
• Study Start: October 1, 2024
• Primary Completion: May 31, 2025
• Study Completion: September 10, 2025
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)