Trials Sponsors Conditions Drugs Pricing

Conditions

Crohn Disease Nutrition Disorders Surgery

Keywords

Crohn's diseaseExclusive enteral nutritionsurgery

Outcome Measures

Primary Outcomes (1)

The change of CRP/ALB level
The ratio of C-reactive protein to albumin level changed after exclusive enteral nutrition.
6 weeks

Secondary Outcomes (4)

BMI
6 weeks
CDAI
6 weeks
postoperative complications
6 weeks
adverse reaction
6 weeks

Study Arms (2)

SED patient

EXPERIMENTAL

SED patients who received semi-elemental exclusive enteral nutrition.

Dietary Supplement: peptison liquid

PD patient

PLACEBO COMPARATOR

PD patients who received polymeric exclusive enteral nutrition.

Dietary Supplement: Enteral nutritional suspension

Interventions

peptison liquidDietary supplement

CD patients requiring bowel resection and preoperative EEN were randomized to receive peptison liquid for 6 weeks.

Also known as: Nutricia, Amsterdam, Netherlands

SED patient

Enteral nutritional suspensionDietary supplement

CD patients requiring bowel resection and preoperative EEN were randomized to receive enteral nutritional suspension for 6 weeks.

Eligibility Criteria

Age18 Years - 65 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

elective bowel resection for Crohn's disease;
preoperative diagnosis of Crohn's disease;

Sponsors & Collaborators

Wei Zhou
Otherlead

Study Sites (1)

Wei Zhou

Hangzhou, Zhejiang, 310016, China

Xiaolong GeCONTACT+86-13867106984 gxlmed@zju.edu.cn

MeSH Terms

Conditions

Crohn DiseaseNutrition Disorders

Condition Hierarchy (Ancestors)

Inflammatory Bowel DiseasesGastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal DiseasesNutritional and Metabolic Diseases

Study Officials

Xiujun Cai
Sir Run Run Shaw Hospital
STUDY CHAIR

Central Study Contacts

Wei Zhou

CONTACT

+8613588706479 zhouweisrrs@zju.edu.cn

Xiaolong Ge

CONTACT

+8613867106984

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: DOUBLE
Who Masked: PARTICIPANT, INVESTIGATOR
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Clinical Professor

Study Record Dates

First Submitted

September 3, 2024

First Posted

September 19, 2024

Study Start

October 1, 2024

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

Semi-elemental Versus Polymeric EEN in the Preoperative Optimization for Patients with CD

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

SED patient

PD patient

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

SED patient

PD patient

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations