The Impact of Preoperative Supplementation of Zinc
1 other identifier
interventional
1
1 country
1
Brief Summary
- 1.Pre operative anthropometric assessment including : weight in kg, height/length and BMI
- 2.Pre operative Zinc supplementation (dose according to the age) for 7 days preoperatively for cases
- 3.Postoperative data collection
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable surgery
Started Apr 2023
Shorter than P25 for not_applicable surgery
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 2, 2023
CompletedFirst Posted
Study publicly available on registry
March 27, 2023
CompletedStudy Start
First participant enrolled
April 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
July 2, 2023
CompletedFebruary 9, 2024
February 1, 2024
3 months
March 2, 2023
February 8, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
The effect of preoerative Zinc supplementation on the hospital length stay in children operated for Hirschsprung's disease
Children oprated for elective surgery for Hirschsprung's disease will be supplemented with zinc seven days before surgery and postoperative data as the duration of hospital length stay in hours will be meausred in both the cases and control groups and comapred.
zinc supplemenation for one week
Study Arms (2)
Interventional
EXPERIMENTAL25 children diagnosed with Hirschsprung disease and planned for elective surgery will be supplemented with Zinc 7 days before the operation . Outcomes will be evaluated thorugh measuring the hospital length stay. Other parameters including inflammatory markers as CRP , CRP /albumin ratio and development of postoperative complications will be assesed and compared between cases and controls
Control
NO INTERVENTION25 children diagnosed with Hirschsprung disease and planned for elective surgery will recieve the standard care provided for the cases and will not be supplemented with Zinc . Outcomes will be evaluated thorugh measuring the hospital length. Other parameters including inflammatory markers as CRP , CRP /albumin ratio and development of postoperative complications will be assesed and compared between cases and controls
Interventions
Eligibility Criteria
You may qualify if:
- All children patients with Hirschsprung disease admitted for surgical intervention with different ( age , sex )
- Type of surgery : transanal pull through
- Whose parents or caregivers approve for the participation in the study
You may not qualify if:
- Patients with emergency situations
- Whose parents or caregivers will not apply for the participation in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Hoda Atef Abdelsattar Ibrahim
Cairo, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- SINGLE
- Who Masked
- CARE PROVIDER
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of Pediatrics
Study Record Dates
First Submitted
March 2, 2023
First Posted
March 27, 2023
Study Start
April 1, 2023
Primary Completion
June 30, 2023
Study Completion
July 2, 2023
Last Updated
February 9, 2024
Record last verified: 2024-02
Data Sharing
- IPD Sharing
- Will not share
Anonoymus data can be reproduced