BAR As a Mortality Predictor in Septic AKI

NCT06584149 | Completed

• 1 other identifier: BAR in septic AKI
• Study Type: observational
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the prognostic value of Blood Urea Nitrogen to serum Albumin ratio in septic Acute Kidney Injury patients Follow-up will be conducted for all enrolled patients for 30 days from admission to record mortality and the cause of death.

Conditions

Acute Kidney Injury; Sepsis

Outcome Measures

Primary Outcomes (1)

• mortality

  number of cases of mortality

  30 days

Secondary Outcomes (5)

• mechanical ventilation

  30 days

• stage-3 AKI

  30 days

• renal replacement therapy

  30 days

• septic shock

  30 days

• length of ICU stay

  30 days

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

This prospective study will be conducted on patients with septic acute kidney injury. After admission of the patient to ICU in Ain Shams University Hospitals

You may qualify if:

• years of age
• Fulfilled the diagnostic criteria of Sepsis 3.0 (defined as a suspected or confirmed infection with a sequential organ failure assessment (SOFA) score of 2 or higher)
• Developed AKI during hospitalization according to Kidney Disease: Improving Global Outcomes (KDIGO) guideline

You may not qualify if:

• ICU length of stay\<24 h
• AKI occurred before current hospital admission.
• AKI is supposed to be secondary to causes other than sepsis.
• Receiving renal replacement therapy at the time of admission.
• Diagnosis with chronic kidney disease.
• Diagnosis with liver failure.
• Pregnant or lactating.
• There was insufficient data for analysis.
• Patients who had received Human serum Albumin infusion 3 days before ICU admission.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Abbassia, 11566, Egypt

Location

MeSH Terms

Conditions

Acute Kidney Injury; Sepsis

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 24, 2024
• First Posted: September 4, 2024
• Study Start: September 25, 2023
• Primary Completion: June 1, 2024
• Study Completion: September 25, 2024
• Last Updated: February 17, 2025

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)