Nutritional Status in Patients With Chronic Kidney Disease
Nutritional Status and Nutritional Problems in Patients With Chronic Kidney Disease Treated With Hemodialysis
2 other identifiers
observational
69
1 country
1
Brief Summary
The goal of this observational study is to investigate how the GLIM criteria\* for the diagnosis of malnutrition should be operationalized in patients with chronic kidney disease (CKD) treated with hemodialysis. The main questions it aims to answer are:
- How can malnutrition be defined when applying different combinations and operationalization strategies of the GLIM criteria?
- How can information from other nutrition assessment tools be used in the operationalization of GLIM?
- Which combinations and operationalization strategies of the GLIM criteria can best predict deterioration in quality of life, muscle strength, and increased mortality? An observational study on patients with CKD in hemodialysis will be performed. Variables will be extracted from the Swedish renal registry, SNR and medical records at two hemodialysis units at one university hospital in Sweden. With start in the fall of 2024, data will be collected during two timepoints (baseline and follow-up) when wanted variables for this study are routinely measured at the units.
- The Global Leadership Initiative on Malnutrition (GLIM) criteria to diagnose malnutrition in adults
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Aug 2024
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 21, 2024
CompletedFirst Submitted
Initial submission to the registry
August 28, 2024
CompletedFirst Posted
Study publicly available on registry
August 30, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2027
September 26, 2025
September 1, 2025
1.8 years
August 28, 2024
September 25, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Malnutrition diagnosis
Malnutition diagnosis according to GLIM
From Aug/Sept 2024 to May 2025
Secondary Outcomes (4)
Overall survival
From Aug/Sept 2024 to Dec 28
Muscle strength
From Aug/Sept 2024 to May 2025
Health related quality of life
Aug/Sept 2024 (baseline)
Muscle mass
From Aug/Sept 2024 to May 2025
Eligibility Criteria
Patients with Chronic Kidney Disease (CKD) treated with hemodialysis at one university hospital in Sweden.
You may qualify if:
- age ≥18 years
- dialysis duration \>3 months prior to recruitment
You may not qualify if:
- patients who only have a dialysis frequency of once a week
- patients treated with a combination of peritoneal dialysis and hemodialysis or treated at home
- patients were written consent cannot be obtained due to medical or mental illness or weakened state of health
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Umeå Universitylead
- Uppsala University Hospitalcollaborator
Study Sites (1)
Uppsala University hospital
Uppsala, Sweden
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sandra Einarsson, PhD
Umeå University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 28, 2024
First Posted
August 30, 2024
Study Start
August 21, 2024
Primary Completion (Estimated)
June 1, 2026
Study Completion (Estimated)
December 1, 2027
Last Updated
September 26, 2025
Record last verified: 2025-09