NCT06569121

Brief Summary

Investigators will conduct a randomized controlled trial (RCT) to assess intervention efficacy of telehealth delivery of the GLB-CVA (tGLB-CVA) compared to a 6-month wait-list control (WLC) in partnership with a diverse group of patient partners and peer mentors.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
94

participants targeted

Target at P50-P75 for not_applicable

Timeline
45mo left

Started Dec 2024

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress28%
Dec 2024Dec 2029

First Submitted

Initial submission to the registry

August 20, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 23, 2024

Completed
4 months until next milestone

Study Start

First participant enrolled

December 7, 2024

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2027

Expected
2.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2029

Last Updated

January 21, 2026

Status Verified

January 1, 2025

Enrollment Period

2.7 years

First QC Date

August 20, 2024

Last Update Submit

January 19, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Body Weight

    Body weight (lbs) will be captured via self-weighing using provided BodyTrace Smart Scale, which includes cellular connectivity so weight will be sent directly to the research team. The scales have demonstrated good concordance rates with self-weighing in previous research. Scales will be setup by the research team before being mailed to participants with instructions.

    Baseline, 3, 6, 9, 12, 18 month

Secondary Outcomes (21)

  • Circumference

    Baseline, 3, 6, 9, 12, 18 month

  • Height

    Baseline, 3, 6, 9, 12, 18 month

  • Body Mass Index (BMI)

    Baseline, 3, 6, 9, 12, 18 month

  • Blood pressure

    Baseline, 3, 6, 9, 12, 18 month

  • Blood Sugar, Hemoglobin A1c (HbA1c)

    Baseline, 3, 6, 9, 12, 18 month

  • +16 more secondary outcomes

Study Arms (2)

Wait List Control (WLC)

NO INTERVENTION

Participants randomized to the wait list control (WLC) will begin the telehealth Group Lifestyle Balance for People post stroke (tGLB-CVA) intervention 6 months after enrolling into the study and completing a baseline assessment.

Telehealth Group LIfestyle Balance for People with Stroke (tGLB-CVA)

EXPERIMENTAL

The telehealth Group Lifestyle Balance for People post stroke (tGLB-CVA) is a one-year program with 22 sessions. The tGLB-CVA is a modification of the Diabetes Prevention Program Group Lifestyle Balance (DPP-GLB) developed by the University of Pittsburgh Diabetes Prevention Support Center (DPSC). It begins with 12 weekly sessions called the Core Program, followed by a Transition phase consisting of 2 bi-weekly and 2 monthly sessions, and a Support Phase consisting of 6 monthly sessions. The goal of the tGLB-CVA program is to help the participant achieve and maintain a 5-7% weight-loss through healthy eating and physical activity.

Behavioral: Group Lifestyle Balance for People Post Stroke (GLB-CVA)

Interventions

12-month healthy lifestyle and weight loss program modified from the Diabetes Prevention Program Group Lifestyle Balance (DPP-GLB)

Telehealth Group LIfestyle Balance for People with Stroke (tGLB-CVA)

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body Mass Index ≥25
  • All types of stroke
  • Able to Participate in Physical Activity
  • ≥12 months post first stroke
  • Have internet, phone, or computer access, or be willing to use one provided by the study team

You may not qualify if:

  • Contraindications for physical activity
  • Low Cognitive Function
  • Residing in hospital, acute rehab, skilled nursing facility
  • Not fluent in the English language
  • Pre-existing eating disorder
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Baylor Scott & White Research Institute

Dallas, Texas, 75204, United States

RECRUITING

MeSH Terms

Conditions

StrokeMyocardial Infarction

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesMyocardial IschemiaHeart DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 20, 2024

First Posted

August 23, 2024

Study Start

December 7, 2024

Primary Completion (Estimated)

August 31, 2027

Study Completion (Estimated)

December 31, 2029

Last Updated

January 21, 2026

Record last verified: 2025-01

Locations