NCT06567873

Brief Summary

The aim of this study is to perform bedside gastric point of care ultrasound (POCUS) exams to assess the gastric volume and content (clear liquids vs solid food) perioperatively in patients who report cannabis use.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started May 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 20, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 23, 2024

Completed
9 months until next milestone

Study Start

First participant enrolled

May 9, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 13, 2025

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 14, 2025

Completed
Last Updated

December 16, 2025

Status Verified

November 1, 2025

Enrollment Period

5 months

First QC Date

August 20, 2024

Last Update Submit

December 9, 2025

Conditions

Gastric UltrasoundPoint of Care UltrasoundCannabis Use

Keywords

cannabisgastric ultrasound

Outcome Measures

Primary Outcomes (1)

  • Incidence of delayed gastric emptying

    A full stomach on gastric ultrasound is defined by the presence of either solid food, thick liquids, or a specific volume (\>1.5 ml/kg) of clear liquids on gastric ultrasound.

    This will be measured pre-operatively in the holding room area.

Secondary Outcomes (3)

  • Nothing by mouth (NPO) intervals

    This will be measured pre-operatively in the holding room area.

  • Presence of gastric peristalsis

    This will be measured pre-operatively in the holding room area.

  • Time interval since last cannabis use

    This will be measured pre-operatively in the holding room area.

Study Arms (1)

Cannabis Users

The cannabis user group will be comprised of patients who report preoperative cannabis use within 1 month of surgery date. This group will receive the ultrasound exam to assess stomach contents.

Other: Gastric Ultrasound Exam

Interventions

Gastric Ultrasound ExamOTHER

A gastric ultrasound is a simple, fast, non-invasive bedside diagnostic test that provides a qualitative and quantitative assessment of gastric contents. There are no known risks of a gastric ultrasound exam.

Cannabis Users

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population will be comprised of patients scheduled for surgery at HSS who meet the following inclusion criteria and none of the exclusion criteria.

You may qualify if:

  • Any patient reporting preoperative cannabis usage within 1 month of surgery date

You may not qualify if:

  • Patient refusal to participate
  • Patient with gastric bypass or any other gastric surgery
  • Large hiatal hernia
  • Patients with large ascites
  • Patients on peritoneal dialysis
  • Emergency surgery
  • Pre-existing diagnosis of gastroparesis
  • Parkinson's disease
  • Diabetes
  • Currently taking metformin
  • Chronic kidney disease stage 3 or higher
  • Creatinine ≥ 1.2
  • Esophageal surgery
  • Currently taking GLP1 agonist medication

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital for Special Surgery

New York, New York, 10021, United States

Location

Related Publications (4)

  • King DD, Stewart SA, Collins-Yoder A, Fleckner T, Price LL. Anesthesia for Patients Who Self-Report Cannabis (Marijuana) Use Before Esophagogastroduodenoscopy: A Retrospective Review. AANA J. 2021 Jun;89(3):205-212.

    PMID: 34042571BACKGROUND

  • Cammarano CA, Villaluz JE. A Reason to Rethink Fasting Guidelines? Marijuana-Induced Gastroparesis and the Implications for Aspiration Risk in the Nil Per Os (NPO) Patient: A Case Report. Am J Case Rep. 2021 Nov 29;22:e934187. doi: 10.12659/AJCR.934187.

    PMID: 34840324BACKGROUND

  • McCallum RW, Soykan I, Sridhar KR, Ricci DA, Lange RC, Plankey MW. Delta-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: a double-blind, randomized study. Aliment Pharmacol Ther. 1999 Jan;13(1):77-80. doi: 10.1046/j.1365-2036.1999.00441.x.

    PMID: 9892882BACKGROUND

  • Esfandyari T, Camilleri M, Ferber I, Burton D, Baxter K, Zinsmeister AR. Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study. Neurogastroenterol Motil. 2006 Sep;18(9):831-8. doi: 10.1111/j.1365-2982.2006.00834.x.

    PMID: 16918762BACKGROUND

MeSH Terms

Conditions

Marijuana Abuse

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Study Officials

  • Oliver Panzer, MD

    Hospital for Special Surgery, New York

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 20, 2024

First Posted

August 23, 2024

Study Start

May 9, 2025

Primary Completion

October 13, 2025

Study Completion

October 14, 2025

Last Updated

December 16, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will not share

Locations

US(1)