NCT06565221

Brief Summary

Determine whether passive heating intervention effects microvascular blood flow as measured with near-infrared spectroscopy

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
4mo left

Started Aug 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 19, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 21, 2024

Completed
1.9 years until next milestone

Study Start

First participant enrolled

August 1, 2026

Expected
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

March 13, 2026

Status Verified

March 1, 2026

Enrollment Period

4 months

First QC Date

August 19, 2024

Last Update Submit

March 11, 2026

Conditions

Blood Flow

Outcome Measures

Primary Outcomes (1)

  • Microvascular blood flow volume

    Measured using NIRS

    Baseline and during intervention

Study Arms (1)

Heat and negative pressure

EXPERIMENTAL

Forearm and quadriceps blood flow at baseline and during intervention

Device: Heat and negative pressure

Interventions

Heat and negative pressureDEVICE

Heat and negative pressure applied to the feet

Heat and negative pressure

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • between 18 and 50 years

You may not qualify if:

  • Diagnosis of peripheral neuropathy
  • open wounds on feet

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Jeff Moore Moore

CONTACT

714-658-7215Jmoore714@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 19, 2024

First Posted

August 21, 2024

Study Start (Estimated)

August 1, 2026

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

March 13, 2026

Record last verified: 2026-03