Are Exercise Capacity and Physical Fitness Related With Quality of Life, Physical Activity, Cognitive Health and Health Literacy in Dyslipidemia

NCT06563154 | Completed

• 1 other identifier: 03-01-2023-4
• Study Type: observational
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

There is insufficient literature explaining the relationship between exercise capacity and physical fitness of dyslipidemia patients and quality of life, cognitive status and health literacy. Our aim with this study is to provide more information to the scientific literature about the relationship between exercise capacity and physical fitness and quality of life and health literacy in dyslipidemia patients.

Conditions

Dyslipidemias

Keywords

Dyslipidemia; Exercise Capacity; Physical Fitness; Cognitive Health; Physical Activity; Health Literacy

Outcome Measures

Primary Outcomes (2)

• Exercise Capacity

  First Day

• Physical Fitness

  Second Day

Secondary Outcomes (4)

• Physical Activity

  Second Day

• Quality of Life Assessment

  Second Day

• Cognitive Health

  Second Day

• Health Literacy

  Second Day

Study Arms (1)

Patient Group

Diagnostic Test: Exercise Capacity Assessment; Diagnostic Test: Physical Fitness Assessment; Other: Quality of Life Assessment; Other: Physical Activity Assessment; Other: Cognitive Health Assessment; Other: Health Literacy Assessment

Interventions

Exercise Capacity Assessment DIAGNOSTIC_TEST

To examine the relationship between exercise capacity and physical fitness of dyslipidemia patients and quality of life, cognitive status and health literacy.

Patient Group

Physical Fitness Assessment DIAGNOSTIC_TEST

* 1-Minute Sit-to-Stand Test: Participants will be asked to sit down and stand up for 1 minute without pausing, and the repetition number will be recorded. * Timed Up-and-Go Test: Participants will be asked to get up, walk a distance of 3 meters, return and sit down again. The time spent during this track will be recorded. * Peripheral muscle strength assessment: Participants will be asked to resist the resistance by producing maximum isometric force during the movement, and the maximal force will be evaluated with a dynamometer. The quadriceps femoris muscle, shoulder abductor muscles and hand grip strength will be used for the assessment. * Flexibility assessment: Participants will be asked to reach towards the tips of their toes while sitting. During this time, the distance between the participant's fingertips and toes will be measured.

Patient Group

Quality of Life Assessment OTHER

Participants' quality of life will be assessed with the Turkish version of the Short Form Quality of Life Questionnaire (SF-36). The questionnaire consists of 36 questions that examine quality of life from different perspectives. It examines quality of life in the subcategories of physical function, physical role difficulty, pain, general health, vitality (energy), social function, emotional role difficulty and mental health. The score for each category varies between 0-100, with a high score indicating a good quality of life.

Patient Group

Physical Activity Assessment OTHER

Participants' physical activity level will be assessed with the Turkish version of the International Physical Activity Scale - Short Form (IPAQ-SF). The IPAQ-SF evaluates the physical activities of the participants in the last 7 days based on sitting time, walking time, moderate and vigorous physical activities.

Patient Group

Cognitive Health Assessment OTHER

Participants' cognitive health will be assessed with the with the Turkish version of the Mini Mental State Examine (MMSE). The test is scored between 0-30. Scores of 25 and above are considered normal. A total score of less than 10 indicates severe impairment. Scores between 10-19 indicate moderate dementia. Scores between 19-24 indicate early dementia.

Patient Group

Health Literacy Assessment OTHER

Participants' health literacy will be assessed with the Turkish version of the HLS-EU-47 health literacy survey. The survey consists of 47 questions. Each item is assessed with one of the following options: Very difficult (1), difficult (2), easy (3), very easy (4) and I don't know. A high total score indicates good health literacy. A total score of 0-25 points indicates insufficient health literacy, \>25-33: problematic - limited health literacy, \>33-42: sufficient health literacy, \>42-50: excellent health literacy.

Patient Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with dyslipidemia

You may qualify if:

• Being followed up with a diagnosis of dyslipidemia,
• Being between the ages of 18-65,
• Being willing to participate in the study.

You may not qualify if:

• Having an orthopedic, neurological, cardiac, pulmonary or rheumatological disease that may affect functional capacity,
• Having a psychiatric disorder that may affect cooperation,
• Refusing to participate in the study.

Sponsors & Collaborators

• Çankırı Karatekin University: lead
• Hacettepe University: collaborator

Study Sites (1)

Hacettepe University

Ankara, Turkey (Türkiye)

Location

Related Publications (1)

• Ozdemir F, Saglam M, Uyaroglu OA, Vardar Yagli N. Impact of physical activity, health literacy and cognitive health on quality of life in dyslipidemia: an observational study. Sci Rep. 2025 Oct 13;15(1):35586. doi: 10.1038/s41598-025-02223-4.

  PMID: 41083504 DERIVED

MeSH Terms

Conditions

Dyslipidemias; Motor Activity

Condition Hierarchy (Ancestors)

Lipid Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Behavior

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: August 17, 2024
• First Posted: August 20, 2024
• Study Start: August 20, 2024
• Primary Completion: December 15, 2024
• Study Completion: December 30, 2024
• Last Updated: January 10, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)