NCT04772443

Brief Summary

The purpose of this study is to determine the efficacy and safety of DWJ1506 and DWJ1507 in the patients with dyslipidemia.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
280

participants targeted

Target at P50-P75 for phase_3

Timeline
Completed

Started Feb 2021

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2021

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

February 24, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 26, 2021

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2022

Completed
Last Updated

February 26, 2021

Status Verified

February 1, 2021

Enrollment Period

1.8 years

First QC Date

February 24, 2021

Last Update Submit

February 24, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • LDL-C levels at week 8

    Change from baseline in LDL-C level at week 8 after administration of the IP

    Week 8

Study Arms (4)

DWJ1506

EXPERIMENTAL
Drug: DWJ1506

DWJ1507

EXPERIMENTAL
Drug: DWJ1507

DWC202011

ACTIVE COMPARATOR
Drug: DWC202011

DWJ1177

ACTIVE COMPARATOR
Drug: DWJ1177

Interventions

DWJ1506

DWJ1506

DWJ1507

DWJ1507

DWC202011

DWC202011

DWC202011

DWJ1177

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged 19 years or over
  • Patients with LDL-C levels ≤ 250 mg/dL, TG \< 500 mg/dL
  • Subjects who voluntarily decided to participate and provided written consent after being told of the objectives, method, and effects of this study

You may not qualify if:

  • Severe congestive hear failure
  • Current active liver disease
  • The use of prohibiterd concomitant therapies
  • Severe gastrointestinal diseases: active ulcer, gastrointestinal or rectal bleeding, active inflammatory bowel syndrome, biliary duct obstruction, active gastritis that is not controlled by medication, etc.
  • Women who were of childbearing potential without contraception, pregnant, or breastfeeding

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Dyslipidemias

Condition Hierarchy (Ancestors)

Lipid Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 24, 2021

First Posted

February 26, 2021

Study Start

February 1, 2021

Primary Completion

December 1, 2022

Study Completion

December 1, 2022

Last Updated

February 26, 2021

Record last verified: 2021-02

Data Sharing

IPD Sharing
Will share