NCT06562322

Brief Summary

Photobiomodulation therapy (PBMT) has recently been indicated as a potential therapeutic strategy in diverse health and sports contexts. However, its efficacy on muscle performance in female futsal players remains unknown. The purpose of this study was to investigate the dose-response effect of PBMT on muscle performance in female futsal players.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 15, 2024

Completed
29 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 15, 2024

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 18, 2024

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 16, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 20, 2024

Completed
Last Updated

January 9, 2026

Status Verified

August 1, 2024

Enrollment Period

29 days

First QC Date

August 16, 2024

Last Update Submit

January 7, 2026

Conditions

Keywords

Physical testPhotobiomodulation therapyFutsalLight-emitting diodesMuscle powerMuscle strength

Outcome Measures

Primary Outcomes (5)

  • Repetitions-to-failure

    The repetitions-to-failure test in the 45º leg press exercise consists of 3 sets at 70% of 1RM, with a 60-s rest interval between each set. Participants will perform as many repetitions as possible until momentary failure (i.e., when the participant is unable to complete the concentric portion of their current repetition across the full range of motion despite using maximal effort), and the maximum number of repetitions in each set will be recorded.

    10 minutes

  • Fatigue index (FI)

    The fatigue index (FI) will be determined by the equation: \[(REPS3 - REPS1)/REPS1\]\*100, where: REPS3 = number of repetitions in set 3, multiplied by the load lifted, and REPS1 = number of repetitions in set 1, multiplied by the load lifted. The higher the FI value (%), the higher the level of muscle fatigue.

    10 minutes

  • Rating of perceive exterion (RPE)

    Rating of perceived exertion (RPE) will be recorded immediately after completion of each set using the OMNI-RES scale. The participants will be instructed to report the perceived exertion value by indicating a number on the OMNI-RES scale (0 for ''no effort'' and 10 for ''maximal effort'') that best represented their momentary exertion.

    10 minutes

  • Countermovement vertical jump (CMJ)

    The CMJ test will be performed on a force platform (BIOMEC400-412, EMG System to Brazil Ltda, São Paulo, Brazil) to assess the flight time. Participants will perform three CMJs, interspersed with 1 min of rest, and the highest flight time will be used as an indicator of muscle power. The test will began with the participant standing, knees extended, and hands fixed on the iliac crest region (hips). The participant then will flexed their legs at an angle of approximately 90º and then quickly extended their legs to maximize the height of the jump. Hands will be kepted on hips throughout the jump.

    10 minutes

  • Maximum voluntary isometric contraction (MVIC)

    The MVIC test for the leg extension exercise (bilateral) will be performed using an isometric dynamometer (CEFISE Biotechnology, São Carlos, Brazil). Briefly, participants will perform three MVICs at 120º of knee flexion (180º = full extension) lasting 5 s, interspersed with 5 s of rest. Participants will be instructed and verbally encouraged to exert maximum force during all attempts. The highest value obtained for peak and mean torque of the three MVICs will be used for the analysis.

    10 minutes

Study Arms (4)

placebo PBMT

PLACEBO COMPARATOR

Participants will be received placebo PBMT immediately before physical tests.

Device: Placebo

300 J PBMT

ACTIVE COMPARATOR

Participants will be received PBMT at 300 J immediately before physical tests.

Device: 300 J

600 J PBMT

ACTIVE COMPARATOR

Participants will be received PBMT at 600 J immediately before physical tests.

Device: 600 J

1260 J PBMT

ACTIVE COMPARATOR

Participants will be received PBMT at 1260 J immediately before physical tests.

Device: 1260 J

Interventions

PlaceboDEVICE

Participants will be received placebo PBMT on the quadriceps muscle of both legs, immediately before physical tests, using a device containing 200 LEDs (100 red and 100 infrared)

placebo PBMT
300 JDEVICE

Participants will be received PBMT at 300 J on the quadriceps muscle of both legs, immediately before physical tests, using a device containing 200 LEDs (100 red and 100 infrared)

300 J PBMT
600 JDEVICE

Participants will be received PBMT at 600 J on the quadriceps muscle of both legs, immediately before physical tests, using a device containing 200 LEDs (100 red and 100 infrared)

600 J PBMT
1260 JDEVICE

Participants will be received PBMT at 1260 J on the quadriceps muscle of both legs, immediately before physical tests, using a device containing 200 LEDs (100 red and 100 infrared)

1260 J PBMT

Eligibility Criteria

Age18 Years - 35 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 18 and 35 years
  • Playing futsal regularly for more than 1 year.

You may not qualify if:

  • Use of any ergogenic or anabolic supplement within 6 months prior to the start of the study,
  • Take any medication that may affect the ability to perform the physical tests,
  • Have any physical limitation (e.g. joint or muscle injury) that may affect the ability to perform the physical test,
  • Be engaged in a restricted diet program (e.g. weight loss diet),
  • Have any skin sensitivity or diseases (e.g. erysipelas, eczema, dermatitis, psoriasis and urticaria) in the irradiated area that may be aggravated by PBMT.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidade Norte do Paraná

Londrina, Paraná, 86.041-140, Brazil

Location

Related Publications (3)

  • Steele J, Fisher J, Giessing J, Gentil P. Clarity in reporting terminology and definitions of set endpoints in resistance training. Muscle Nerve. 2017 Sep;56(3):368-374. doi: 10.1002/mus.25557. Epub 2017 Apr 1.

    PMID: 28044366BACKGROUND
  • Robertson RJ, Goss FL, Rutkowski J, Lenz B, Dixon C, Timmer J, Frazee K, Dube J, Andreacci J. Concurrent validation of the OMNI perceived exertion scale for resistance exercise. Med Sci Sports Exerc. 2003 Feb;35(2):333-41. doi: 10.1249/01.MSS.0000048831.15016.2A.

    PMID: 12569225BACKGROUND
  • Luque MZ, Aguiar AF, da Silva-Araujo AK, Zaninelli TH, Heintz OK, Saraiva-Santos T, Bertozzi MM, Souza NA, Junior EO, Verri WA Jr, Borghi SM. Evaluation of a preemptive intervention regimen with hesperidin methyl chalcone in delayed-onset muscle soreness in young adults: a randomized, double-blinded, and placebo-controlled trial study. Eur J Appl Physiol. 2023 Sep;123(9):1949-1964. doi: 10.1007/s00421-023-05207-2. Epub 2023 Apr 29.

    PMID: 37119360BACKGROUND

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Model Details: Crossover
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

August 16, 2024

First Posted

August 20, 2024

Study Start

February 15, 2024

Primary Completion

March 15, 2024

Study Completion

March 18, 2024

Last Updated

January 9, 2026

Record last verified: 2024-08

Data Sharing

IPD Sharing
Will not share

Locations