Light Reflection on Human Skin in Whole-Body Photobiomodulation Therapy

NCT06866522 | Recruiting

• 2 other identifiers: 70368823.8.0000.55042023/07857-6
• Study Type: interventional
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Photobiomodulation therapy (PBMT) is based on exposing biological tissues to low-intensity light, with effects depending on the light-tissue interaction. When irradiated without skin contact, part of the incident light is reflected and lost. In this context, the amount of reflected light in PBMT applied without skin contact, as well as the influence of skin phototype, has not yet been established. Objective: To quantify the reflection of light from PBMT on the skin of men and women aged 18 to 30 years, considering skin phototypes. Methodology: Participants will be divided into three groups based on skin phototype (Group 1: phototypes I and II; Group 2: phototypes III and IV; Group 3: phototypes V and VI) and sex. They will be subjected to whole-body PBMT with red light (660 nm; 31.85±3.85 mW; 45.50±5.07 mW/cm²) and infrared light (850 nm; 25.29±2.99 mW; 36.13±4.27 mW/cm²) at 20 cm from the light-emitting source, with measurement of light reflection in the regions of the brachial biceps, abdomen, lumbar, anterior and posterior thigh, and calf using a power and energy analyzer (powermeter PM100D and sensor S130C, 0.7 cm²). Data will be analyzed for normality and groups were compared with a significance level of 5%

Conditions

Photobiomodulation Therapy; Phototype

Keywords

photobiomodulation; low-level laser therapy; skin optics; melanin; light reflection

Outcome Measures

Primary Outcomes (1)

• Light Reflection

  Light reflection will be measured in mW with a PowerMeter Device in the angles of 30º, 60º and 90º considering the participant in front of the whole-body photobiomodulation therapy device.

  Acute measurement. The measurement will be performed just during the light therapy irradiation, on the day of the procedure.

Study Arms (1)

Photobiomodulation Reflection Group

EXPERIMENTAL

This group received measures of the light reflection using a whole-body photobiomodulation therapy with a Joovv device. In this group, participants were subclassified with the Fitzpatrick scale for their phototypes.

Device: Whole-body Photobiomodulation Therapy

Interventions

Whole-body Photobiomodulation Therapy DEVICE

Whole-body Photobiomodulation Therapy applied for approximately 10 minutes, being 5 minutes with the red wavelength and 5 minutes with the infrared wavelength.

Photobiomodulation Reflection Group

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• male and female
• age between 18 and 30 years
• body mass index (BMI) between 18.5 and 29.9 kg/m2.

You may not qualify if:

• tattoo in the light reflection assessment areas
• history of skin cancer
• skin lesions such as open wounds in the mid-thigh, abdomen, biceps brachii, back and calf
• patients with cognitive difficulty reporting thermal sensation

Sponsors & Collaborators

• Universidade Federal de Sao Carlos: lead

Study Sites (1)

Federal University of São Carlos (UFSCar)

São Carlos, São Paulo, 13565-905, Brazil

RECRUITING

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 28, 2025
• First Posted: March 10, 2025
• Study Start: November 27, 2023
• Primary Completion: March 20, 2025
• Study Completion: July 20, 2025
• Last Updated: March 12, 2025

Record last verified: 2025-03

Locations

BR (1)