Race and Socioeconomic Position: Examining Common Social Pathways to Disease Risk

NCT06552702 | Completed

• 1 other identifier: 21044507
• Study Type: observational
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Black Americans and those of lower socioeconomic position (SEP) are at higher risk for multiple diseases of aging and shorter lifespans, but the psychophysiological mechanisms that may account for these effects are not clear. The overarching objective of this pilot grant is to improve our understanding of the proximal social exposures and subsequent psychobiological processes that contribute to racial and socioeconomic health disparities. Precisely understanding what these mutable social and psychological mechanisms are is necessary in order to identify intervention targets at the level of the individual.

Conditions

Healthy Aging

Keywords

socioeconomic status; race; stress; social relationships; ambulatory blood pressure

Outcome Measures

Primary Outcomes (2)

• Ambulatory Systolic Blood Pressure

  Mean

  during four days of ambulatory monitoring

• Ambulatory Diastolic Blood Pressure

  Mean

  during four days of ambulatory monitoring

Study Arms (1)

Community sample

Black Americans (8 high SEP, 8 low SEP) and White Americans (8 high SEP, 8 low SEP) between the ages of 35 and 70

Other: There is no intervention

Interventions

There is no intervention OTHER

There is no intervention.

Community sample

Eligibility Criteria

• Age: 35 Years - 70 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Recruitment will target Black Americans (8 high SEP, 8 low SEP) and White Americans (8 high SEP, 8 low SEP) between the ages of 35 and 70. Low SEP will be defined as a score of 1 to 3 on the MacArthur (ladder) scale of subjective social status (range 1-10), and high SEP as a score of 8-10 on the same scale.

You may qualify if:

• \- Black American or White American between the ages of 35 and 70.

You may not qualify if:

• Conditions that require immediate treatment (e.g., Stage 2 hypertension; resting blood pressure \> 160/100 mmHg)
• Excessive alcohol consumption (\> 5 portions, \> 3 times per week)
• Frequent illicit drug use
• Schizophrenia or bipolar disorder
• Permanent neurological deficit
• Shift work
• Current pregnancy

Sponsors & Collaborators

• University of Alabama, Tuscaloosa: lead
• University of Alabama at Birmingham: collaborator

Study Sites (1)

University of AL Psychology Department

Tuscaloosa, Alabama, 35404, United States

Location

Related Publications (4)

• Jones CP. Levels of racism: a theoretic framework and a gardener's tale. Am J Public Health. 2000 Aug;90(8):1212-5. doi: 10.2105/ajph.90.8.1212.

  PMID: 10936998 BACKGROUND

• Bailey ZD, Krieger N, Agenor M, Graves J, Linos N, Bassett MT. Structural racism and health inequities in the USA: evidence and interventions. Lancet. 2017 Apr 8;389(10077):1453-1463. doi: 10.1016/S0140-6736(17)30569-X.

  PMID: 28402827 BACKGROUND

• Krieger N, Chen JT, Waterman PD, Rehkopf DH, Subramanian SV. Painting a truer picture of US socioeconomic and racial/ethnic health inequalities: the Public Health Disparities Geocoding Project. Am J Public Health. 2005 Feb;95(2):312-23. doi: 10.2105/AJPH.2003.032482.

  PMID: 15671470 BACKGROUND

• Williams DR, Mohammed SA. Racism and Health I: Pathways and Scientific Evidence. Am Behav Sci. 2013 Aug 1;57(8):10.1177/0002764213487340. doi: 10.1177/0002764213487340.

  PMID: 24347666 BACKGROUND

Study Officials

• Jenny Cundiff

  University of Alabama at Birmingham

  PRINCIPAL INVESTIGATOR

• Karlene Ball

  University of Alabama at Birmingham

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 29, 2023
• First Posted: August 14, 2024
• Study Start: March 28, 2022
• Primary Completion: December 16, 2022
• Study Completion: December 16, 2022
• Last Updated: August 14, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)