Dual-task Training in Older Adults

NCT05296551 | Terminated

• 1 other identifier: NCR213528
• Study Type: interventional
• Target: 3
• Locations: 1 country
• Sites: 1

Brief Summary

This study seeks to understand what factors influence the capacity to perform simultaneous motor and cognitive tasks in older adults to improve movement throughout their community with the least risk of injury. To function in the real world, one needs to "walk and talk", or to move about the community while attending to their environment. Navigating a busy environment becomes increasingly difficult due to the multitude of constraints placed on the organism by both the brain and the body that are associated with aging. Resulting lack of movement causes a downward spiral; further decreasing function and increasing risk of co-morbidities. This will impose an enormous cost on our healthcare system as the elderly population continues to grow in the United States. The investigators aim to investigate both cognitive and movement changes during aging to prevent declines in functional mobility. The investigators will do this through eight weeks training of simultaneous cognitive and motor tasks (cognitive-motor training).

Conditions

Healthy Aging

Keywords

Dual-Task; Cognitive-Motor Interference; Functional Mobility; Cognition; Motor Performance

Outcome Measures

Primary Outcomes (3)

• Change in Timed Up and Go Tests in 4 week increments

  Timed Up and Go, and Timed Up and Go Cognitive

  Baseline, Week 4, and Week 8

• Change in 10 meter walk test self-selected pace in 4 week increments

  self selected pace walking over an instrumented mat (ZenoMat) both single task and while counting serial 3's

  Baseline, Week 4, and Week 8

• Change in Cognition in 4 week increments

  Components of Cognitive Fluidity as measured by the NIH Toolbox Cognitive Battery

  Baseline, Week 4, and Week 8

Secondary Outcomes (3)

• Balance Test Performance in 4 week increments

  Baseline, Week 4, and Week 8

• change in 10 meter walk test fast pace in 4 week increments

  Baseline, Week 4, and Week 8

• Change in Muscle Electromyography in 4 week increments

  Baseline, Week 4 and Week 8

Study Arms (3)

Dual Task One

EXPERIMENTAL

Participants perform a cognitive-motor dual-task where the motor task is the same for all groups and the simultaneously performed cognitive task is simple.

Other: Cognitive-motor dual-task

Dual Task Two

EXPERIMENTAL

Participants perform a cognitive-motor dual-task where the motor task is the same for all groups and the simultaneously performed cognitive task is complex.

Other: Cognitive-motor dual-task

Control

ACTIVE COMPARATOR

Participants perform only a motor-task that is the same for all groups (no simultaneous cognitive task).

Other: Motor Task

Interventions

Motor Task OTHER

A visuomotor task is presented where an individual must match their knee to an ellipse that moves up and down on a screen, resulting in a marching-in-place motion at a specified frequency.

Control

Cognitive-motor dual-task OTHER

While performing the "Motor Task" intervention, letters of different colors and orientation randomly appear one at a time on the screen. During the Cognitive-motor dual-task, individuals are instructed to count the number of times that either 1 (simple cognitive task), or 2 (complex cognitive task) characters appear on the screen during the motor task.

Dual Task One; Dual Task Two

Eligibility Criteria

• Age: 60 Years - 95 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Between 60 and 95 Years Old
• Self-described as generally healthy
• Normal or corrected to normal vision
• Able to stand on one foot for at least 3 seconds with minimal sway and no loss of balance

You may not qualify if:

• Known neurologic disorder affecting mobility or cognition
• Self-reported known moderate or greater lower extremity arthritis
• Known disease process that affects muscle function
• Color Blindness
• Lower extremity pain in the previous 15 days
• Known learning or attention deficit
• Currently taking medication that affects attention, learning, and/or memory
• Known Cardiovascular Disease of previous heart attack or cardiomyopathy
• Chronic Kidney Disease
• Severe Obesity as defined by a BMI of greater than or equal to 40 Kg/m2

Sponsors & Collaborators

• George Washington University: lead

Study Sites (1)

The George Washington University, Department of Health, Human Function and Rehabilitation Science

Washington D.C., District of Columbia, 20006, United States

Location

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Study Officials

• Keith Cole, DPT, Ph. D.

  The George Washington University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Model Details: Subjects are block randomized into 3 parallel groups.

Study Record Dates

• First Submitted: March 5, 2022
• First Posted: March 25, 2022
• Study Start: March 3, 2022
• Primary Completion: May 5, 2024
• Study Completion: May 5, 2024
• Last Updated: May 10, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)