Construction of a Cohort for Pan-Vascular Disease Among Employees of Taizhou People's Hospital

NCT06545799 | Not Yet Recruiting DMC

• 1 other identifier: KY 2024-098-01
• Study Type: observational
• Target: 1,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

• High-sensitivity cardiac troponin I and NT-proBNP testing
• Non-invasive arterial stiffness testing
• Measurement of visceral and subcutaneous fat content
• Fundus photography
• Body composition analysis 4 Regular Follow-Up Annual follow-up for a total of 10 years. The follow-up includes:
• . Collection of updated demographic information and medical history, as well as repeated questionnaires on nutrition, physical activity, and smoking habits.
• . Reassessment of the following items:
• High-sensitivity cardiac troponin I and NT-proBNP testing
• Non-invasive arterial stiffness testing
• Measurement of visceral and subcutaneous fat content
• Fundus photography
• Body composition analysis 5 Outcome Evaluation 1）. Primary Outcomes: Cardiovascular mortality, non-fatal myocardial infarction, or non-fatal stroke events. 2）. Secondary Outcomes: All vascular events, changes in cardiovascular biomarkers, and degree of arterial stiffness.

Conditions

Cardiovascular Death; Myocardial Infarction; Stroke

Outcome Measures

Primary Outcomes (1)

• Cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke events

  Cardiovascular death: Death from heart or blood vessel diseases. Non-fatal myocardial infarction: Heart attack that does not result in death. Non-fatal stroke events: Stroke incidents that do not result in death.

  September 2024 to August 2034

Eligibility Criteria

• Age: 45 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Each year, during the annual health check-ups for hospital staff, potential participants are recruited. Those who express interest are provided with a detailed explanation of the study's objectives, content, and procedures, and are required to sign an informed consent form.

You may qualify if:

• Employed or retired individuals aged 45 years or older;
• Willing to sign an informed consent form and voluntarily participate in health examinations and related data collection.

You may not qualify if:

• History of myocardial infarction, ischemic or hemorrhagic stroke, or revascularization of coronary, carotid, or peripheral arteries;
• Employees with severe psychological disorders who are unable to cooperate with the study;
• Pregnant or breastfeeding women.

Sponsors & Collaborators

• Jiangsu Taizhou People's Hospital: lead

Biospecimen

Retention: SAMPLES WITHOUT DNA

2 ml of blood

MeSH Terms

Conditions

Myocardial Infarction; Stroke

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Central Study Contacts

Qingqing Zhang

CONTACT

+86 180 6198 6120; 18061986120@189.cn

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 10 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 30, 2024
• First Posted: August 9, 2024
• Study Start: September 1, 2024
• Primary Completion (Estimated): September 1, 2034
• Study Completion (Estimated): September 1, 2034
• Last Updated: August 9, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share