NCT02824107

Brief Summary

The aim of this study is to identify groups of subjects at risk of recurrence in secondary prevention based on Psychosocial Factors. The aim is also to propose novel levers to reduce health inequalities in this population so as to develop new prevention strategies for neuro- and cardio-vascular health This study is based on data from questionnaires (Quality of life at work, perceived stress, perceived disease severity) and on behavior indicators (factors related to lifestyle: alcohol, smoking, obesity, sedentarity). Biomarkers of endothelial function (ADMA) will also be assayed. It's an interventional study because of blood sample

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
294

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 8, 2016

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

June 29, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 6, 2016

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 26, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 26, 2019

Completed
Last Updated

May 29, 2020

Status Verified

May 1, 2020

Enrollment Period

3.5 years

First QC Date

June 29, 2016

Last Update Submit

May 28, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • number of psychosocial factors (PSF) on the level of risk for neuro-cardiovascular disease.

    through the completion study an average of 6 month

Secondary Outcomes (1)

  • study the proportion of diméthyl-arginine asymetrical (ADMA) in patients with PSF

    1st day

Study Arms (2)

patients with myocardial infarction

EXPERIMENTAL
Biological: blood sampleBehavioral: questionnaires for psychosocial factors

patients with stroke

EXPERIMENTAL
Biological: blood sampleBehavioral: questionnaires for psychosocial factors

Interventions

blood sampleBIOLOGICAL
patients with myocardial infarctionpatients with stroke
patients with myocardial infarctionpatients with stroke

Eligibility Criteria

AgeUp to 65 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who have provided oral consent to participate
  • Patients over 18 years
  • Patients hospitalized for type 1 MI or ischemic stroke/TIA \< 24H after symptom onset
  • Age \< 65 years
  • With a professional activity (INSEE definition) at the time of the neuro or cardiovascular event
  • At least one of the following risk factors: current smoking, obesity (waist circumference \> 88 cm (W)/102 cm (M) or a waist/hip ratio 0.85(W)/0.9(M), sedentarity (physical activity \< 150 min / week), alcohol consumption (\> 3 standard glasses per day for men, \> 2 standard glasses/d for women)

You may not qualify if:

  • Adult under guardianship
  • Patients without national health insurance cover
  • Pregnant or breast-feeding women
  • Clinical state making it impossible to use questionnaires or to measure risk factors
  • Stroke or TIA not related to atheroma or cardioembolism (dissection, hemopathy…)
  • type \> 1 MI

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Hospitalier Universitaire

Dijon, 21079, France

Location

MeSH Terms

Conditions

Myocardial InfarctionStroke

Interventions

Blood Specimen CollectionSurveys and QuestionnairesPsychology

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosisCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative TechniquesData CollectionEpidemiologic MethodsHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public HealthBehavioral SciencesBehavioral Disciplines and Activities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 29, 2016

First Posted

July 6, 2016

Study Start

February 8, 2016

Primary Completion

August 26, 2019

Study Completion

August 26, 2019

Last Updated

May 29, 2020

Record last verified: 2020-05

Locations