Depression and Anxiety Among Chronic Pain Patients in the Netherlands

NCT06545513 | Completed

• 1 other identifier: 2022.0372
• Study Type: observational
• Target: 3,240
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to examine the prevalence of anxiety and depression among patients with chronic pain attending secondary and tertiary pain clinics in the Netherlands. Additionally, the study explores how pain intensity, sociodemographic factors, and the presence of anxiety or depression are associated with quality of life in this population. Using an anonymized dataset provided by the data manager, we aimed to prevent a low response rate at Amsterdam UMC and thereby reduce the risk of non-response bias.

Conditions

Chronic Pain; Depression, Anxiety

Keywords

Chronic pain; Depression; Anxiety

Outcome Measures

Primary Outcomes (1)

• Prevalence of depression

  prevalence of depression among chronic pain patients

  2020-2024

Study Arms (1)

Patients with chronic pain

The patients have completed surveys prior or during their visit at the chronic pain outpatient clinic.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with chronic pain under treatment at chronic pain outpatient clinics at Amsterdam UMC.

Patients over 18 years old with chronic pain, who have been treated at the pain clinic at Amsterdam UMC from 2020 to 2024, will be included in the study, provided they have completed the HADS questionnaires in full. Patients with incomplete HADS questionnaires and those who have filed a general objection to the use of their data for this scientific research will be excluded from participation in the analysis.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• Amsterdam UMC, location VUmc: lead

Study Sites (1)

Amsterdam UMC

Amsterdam, North Holland, 1081HV, Netherlands

Location

Related Publications (4)

• Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur J Pain. 2006 May;10(4):287-333. doi: 10.1016/j.ejpain.2005.06.009. Epub 2005 Aug 10.

  PMID: 16095934 BACKGROUND

• Magni G, Marchetti M, Moreschi C, Merskey H, Luchini SR. Chronic musculoskeletal pain and depressive symptoms in the National Health and Nutrition Examination. I. Epidemiologic follow-up study. Pain. 1993 May;53(2):163-168. doi: 10.1016/0304-3959(93)90076-2.

  PMID: 8336986 BACKGROUND

• Carroll LJ, Cassidy JD, Cote P. Depression as a risk factor for onset of an episode of troublesome neck and low back pain. Pain. 2004 Jan;107(1-2):134-9. doi: 10.1016/j.pain.2003.10.009.

  PMID: 14715399 BACKGROUND

• Racine M. Chronic pain and suicide risk: A comprehensive review. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Dec 20;87(Pt B):269-280. doi: 10.1016/j.pnpbp.2017.08.020. Epub 2017 Aug 26.

  PMID: 28847525 BACKGROUND

Related Links

• International Classification of Disease (11th version)

MeSH Terms

Conditions

Chronic Pain; Depression; Anxiety Disorders

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: August 5, 2024
• First Posted: August 9, 2024
• Study Start: August 30, 2022
• Primary Completion: November 19, 2024
• Study Completion: November 19, 2024
• Last Updated: May 14, 2025

Record last verified: 2025-05

Locations

NL (1)