Blood Flow Restriction Training on Upper Extremity Grip Strength

NCT06535373 | Recruiting

• 1 other identifier: BFRGRIP
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The primary objective of this prospective study is to investigate the effects of Blood Flow Restriction (BFR) training compared to traditional low-weight resistance training on grip strength in young adults. Despite the growing interest in BFR training and its potential benefits, there is limited research specifically investigating its impact on grip strength. Understanding the effects of BFR training on grip strength could have significant implications for individuals seeking to optimize their grip performance, rehabilitation settings, and sports performance enhancement. Additionally, examining the safety and efficacy of BFR training for this specific outcome will contribute valuable insights to the scientific community.

Conditions

Healthy Volunteers

Outcome Measures

Primary Outcomes (1)

• Grip Strength

  Isometric grip strength will be assessed in the dominant arm after the intervention using the Jamar hydraulic hand dynamometer (Lafayette Instruments, Lafayette, IN). Participants will be positioned in sitting with the knees and hips flexed to 90 degrees and feet flat on the floor. The shoulder will be in a neutral position with the elbow flexed to 90 degrees and the forearm in neutral pronation-supination. (Crotin \& Ramsey, 2021) The participant will be instructed to squeeze the dynamometer with maximal effort for 3 seconds while receiving verbal encouragement. A total of three repetitions will be completed with a 30 second rest between trials to reduce fatigue. (Crotin \& Ramsey, 2021) The peak grip strength value of all three trails will be used for baseline strength and 30% of the peak value will be used to calculate the resistance (in lbs.) for the exercise protocol.

  baseline, post-intervention (6 weeks), and follow-up (6 weeks)

Study Arms (2)

Blood flow restriction with low-weight resistance training (LWRT) group

EXPERIMENTAL

a blood flow restriction with low-weight resistance training (LWRT) group

Other: Blood flow restriction

No Blood flow restriction group which just does LWRT

NO INTERVENTION

a non blood flow restriction group which just does low-weight resistance training

Interventions

Blood flow restriction OTHER

Both groups will undergo a 6-week training intervention with training 2x a week, after which grip strength and other relevant outcomes will be measured and compared. Exercise sessions will be at least 48 hours apart. Participants will be allowed to continue with their normal exercise routine outside of the study.

Blood flow restriction with low-weight resistance training (LWRT) group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Participants must be between 18 and 35 years old at the time of enrollment.
• Participants should be in good general health with no known cardiovascular, musculoskeletal, or neurological disorders that could interfere with exercise participation.
• Participants must provide informed consent before enrollment in the study, indicating their willingness to participate voluntarily.

You may not qualify if:

• Participants with a history of cardiovascular disease (e.g., heart disease, hypertension), musculoskeletal injuries (e.g., fractures, dislocations), or neurological disorders (e.g., neuropathy) that could affect exercise performance will be excluded.
• Participants taking medications or supplements that may impact muscle strength, metabolism, or blood flow will be excluded from the study.
• Pregnant individuals will be excluded due to potential risks associated with exercise and blood flow restriction during pregnancy.
• Individuals with recent upper extremity injuries, such as strains, sprains, or fractures, will be excluded until fully recovered.
• Blood Pressure: Participants with uncontrolled high blood pressure or other medical conditions affecting vascular health may be excluded due to potential risks associated with blood flow restriction.

Sponsors & Collaborators

• Casa Colina Hospital and Centers for Healthcare: lead
• Azusa Pacific University: collaborator

Study Sites (1)

Casa Colina Healthcare and Hospital

Pomona, California, 91767, United States

RECRUITING

MeSH Terms

Interventions

Blood Flow Restriction Therapy

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: DIrector of Research

Model Details: This is a randomized controlled study where participants will be randomly assigned to one of two groups.

Study Record Dates

• First Submitted: July 30, 2024
• First Posted: August 2, 2024
• Study Start: August 19, 2024
• Primary Completion: August 1, 2025
• Study Completion: December 1, 2025
• Last Updated: October 15, 2024

Record last verified: 2024-10

Locations

US (1)