Unravelling the Interplay of Weight Stigma and Pregnancy Outcomes: A Prospective Cohort Study

NCT06531694 | Not Yet Recruiting

• 1 other identifier: 601966989
• Study Type: observational
• Target: 800
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this prospective cohort study is to investigate the contribution of stigma and discrimination due to body size to adverse pregnancy outcomes. We also aim to explore the role of psychological and social factors in this relationship. The specific objectives of this study are: Objective 1: Explore weight stigma as a mediator of the association between BMI ≥30 kg/m2 and adverse pregnancy outcomes. Objective 2: Explore confounding factors not previously considered such as weight cycling, trauma, eating disorders, and internalised weight bias as mediators in the relationship between obesity and adverse pregnancy outcomes.

Conditions

Pregnancy Outcomes; Overweight and Obesity; Weight Stigma

Keywords

Prenatal care; Healthcare

Outcome Measures

Primary Outcomes (1)

• Proportion of women diagnosed with gestational diabetes mellitis by 34 weeks gestation

  Measuring the number of women reporting a diagnosis of gestational diabetes mellitis by 34 weeks gestation as assessed via self-reported measures and chart review.

  34 weeks

Secondary Outcomes (5)

• Proportion of women experiencing induction of labour

  6 weeks postpartum

• Proportion of women reporting each mode of birth (i.e., vaginal birth, caesarean section, assisted vaginal birth, or other)

  6 weeks postpartum

• Proportion of women who reported experiencing gestational hypertension in their most recent pregnancy

  6 weeks postpartum

• Infant birth weight (in grams) reported by mothers for their most recent infant

  6 weeks postpartum

• Proportion of women currently breastfeeding their infant reported by mothers at 6-weeks postpartum

  6 weeks postpartum

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: Women who are pregnant between 10-22 weeks gestation
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be pregnant women who are at least 18 years old with a singleton pregnancy, and who are booked in to give birth at Adelaide Women's and Children's Hospital or Royal Women's and Children's Brisbane. At baseline, women must be between 10 and 22 weeks' gestation.

You may qualify if:

• Pregnant between 10-22 weeks' gestation
• Greater or equal than 18 years of age
• Booked to give birth at Adelaide Women's and Children's Hospital or Royal Women's and Children's Brisbane
• Access to the Internet to complete the survey
• Consents to the extraction of hospital electronic medical record data about the woman and relevant to the study.
• Ability to read and understand English

You may not qualify if:

• Pregnant with multiple gestation
• Insufficient English language skills to consent and complete the questionnaires.

Sponsors & Collaborators

• Monash University: lead

MeSH Terms

Conditions

Weight Prejudice; Overweight; Obesity

Condition Hierarchy (Ancestors)

Prejudice; Social Behavior; Behavior; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Briony Hill, PhD

  Monash University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Briony Hill, PhD

CONTACT

+61421012283; briony.hill@monash.edu

Megan Mitchell, PhD

CONTACT

megan.mitchell@adelaide.edu.au

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 7, 2024
• First Posted: August 1, 2024
• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2028
• Last Updated: February 4, 2026

Record last verified: 2026-02