Pilates Versus Eccentric Exercises on Multiple Sclerosis

NCT06524089 | Completed

• 1 other identifier: PILATES 2024
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to determine whether Pilates-based stability or eccentric training is more effective for patients with multiple sclerosis(MS) with chronic non-specific low back pain(NSLBP).

Conditions

Multiple Sclerosis

Keywords

Pilates; eccentric; multiple sclerosis; low back pain

Outcome Measures

Primary Outcomes (2)

• pain intensity

  VAS for measuring pain severity

  At baseline and after 6 week

• Function

  The Trunk impairment scale (TIS) The static subscale investigates: (1) the ability of the subject to maintain a sitting position with feet supported; (2) the ability to maintain a sitting position while the legs are passively crossed, and (3) the ability to maintain a sitting position when the subject crosses the legs actively. The dynamic subscale contains items on lateral flexion of the trunk and unilateral lifting of the hip. To assess the coordination of the trunk, the subject is asked to rotate the upper or lower part of his or her trunk 6 times, initiating the movements either from the shoulder girdle or from the pelvic girdle, respectively. For each item, a 2-, 3- or 4- point ordinal scale is used. On the static and dynamic sitting balance and coordination subscales the maximal scores that can be attained are 7, 10 and 6 points. Therefore, TIS ranges between 0 for a minimal performance to 23 for a perfect performance.

  At baseline and after 6 week

Secondary Outcomes (1)

• back muscle strength

  At baseline and after 6 week

Study Arms (2)

Pilates

EXPERIMENTAL

Fifteen patients will receive Pilates exercises

Other: Pilate training

eccentric

EXPERIMENTAL

Fifteen patients will receives eccentric training

Other: eccentric training

Interventions

Pilate training OTHER

Pilates based training exercises group will perform Pilates divided into two levels (beginner and intermediate). Each level will last for six sessions.

Pilates

eccentric training OTHER

eccentric trunk training exercises group:The course of the intervention period is 12 sessions total, exercises performed for two to three sets with 10 to 15 repetitions each set and 2 min rest between each set

eccentric

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age range 18 to 40 years.
• Relapsing-remitting free for at least 90 days before testing.

You may not qualify if:

• Having a neurologic disease other than MS.
• A relapse within 3 months.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo university hospital

Giza, 12625, Egypt

Location

Related Publications (2)

• Duff WRD, Andrushko JW, Renshaw DW, Chilibeck PD, Farthing JP, Danielson J, Evans CD. Impact of Pilates Exercise in Multiple Sclerosis: A Randomized Controlled Trial. Int J MS Care. 2018 Mar-Apr;20(2):92-100. doi: 10.7224/1537-2073.2017-066.

  PMID: 29670495 BACKGROUND

• Demaneuf T, Aitken Z, Karahalios A, Leong TI, De Livera AM, Jelinek GA, Weiland TJ, Marck CH. Effectiveness of Exercise Interventions for Pain Reduction in People With Multiple Sclerosis: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Arch Phys Med Rehabil. 2019 Jan;100(1):128-139. doi: 10.1016/j.apmr.2018.08.178. Epub 2018 Sep 19.

  PMID: 30240593 BACKGROUND

MeSH Terms

Conditions

Multiple Sclerosis; Low Back Pain

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Karima A Hassan

  Cairo University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Model Details: Parallel group prospective randomized clinical trial

Study Record Dates

• First Submitted: July 22, 2024
• First Posted: July 29, 2024
• Study Start: July 30, 2024
• Primary Completion: March 2, 2025
• Study Completion: March 2, 2025
• Last Updated: March 6, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)