Pilates, Yoga and Tai Chi Exercises' Effect on Balance and Gait in Patients With Multiple Sclerosis

NCT06612138 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/005332
• Study Type: interventional
• Target: 120
• Locations: 0 countries
• Sites: N/A

Brief Summary

this study will be conducted to compare between the effect of Pilates, Yoga and Tai Chi on balance, gait ability, functional mobility and fatigue in patients with multiple sclerosis

Conditions

Multiple Sclerosis

Keywords

pilates; yoga; tai chi; multiple scelerosis

Outcome Measures

Primary Outcomes (3)

• balance

  The Berg Balance Scale (BBS) was developed to measure balance. The BBS consists of 14 functional balance items.Each item is scored on a 5-point ordinal scale ranging from 0 to 4, with 0 indicating an inability to complete the task entirely and 4 indicating an ability to complete the task criterion.A score of 56 indicates functional balance; and scores below 45 indicate greater risk for falling.

  up to six weeks

• gait assessment

  12-Item Multiple Sclerosis Walking Scale is valid and reliable to assess gait ability in patients with multiple sclerosis. Patients are asked to answer 12 questions about limitations to their walking due to MS over the past 2 weeks, circling a number that best describes their degree of restriction (1, not at all; 2, a little; 3, moderately; 4, quite a bit; 5, extremely). Higher scores indicate the higher impact of the disease on walking. Finally, the score of walking ability falls into a 48-point range with minimum and maximum scores of 12 and 60.

  up to six weeks

• exercise capacity

  6 Minute Walk Test is valid and reliable for the evaluation of exercise capacity.The patient is instructed to 'walk at your comfortable pace' back and forth along a hallway for 6 minutes. The maximum distance walked is measured and recorded

  up to six weeks

Secondary Outcomes (3)

• functional mobility

  up to six weeks

• fatigue

  up to six weeks

• life disability

  up to six weeks

Study Arms (4)

Pilates exercises

EXPERIMENTAL

the patients will receive pilates exercise twice a week for six weeks plus traditional

Other: pilates exercises; Other: tradional physical therapy

yoga exercise

EXPERIMENTAL

the patients will receive yoga exercise twice a week for six weeks plus traditional

Other: yoga exercises; Other: tradional physical therapy

tai chi exercises

EXPERIMENTAL

the patients will receive tai chi exercise twice a week for six weeks plus traditional

Other: tai chi exercises; Other: tradional physical therapy

traditional physical therapy

ACTIVE COMPARATOR

the patients will receive tradional physical therapy twice a week for six weeks

Other: tradional physical therapy

Interventions

pilates exercises OTHER

the patients will receive pilates exercises in the form of breathing exercises, chest lift, bridging, mermaid, swan, quadruped exercises

Pilates exercises

yoga exercises OTHER

the patients will receive yoga in the form of Bhastrikā: rapid and powerful inhalations and exhalations by means of the force of the diaphragm, letting the air sound when exhaling, Nāḏī Śoḏhana: from Sanskrit, "nadi" means \'to channel\' and "shodhana" means \'purify, cleanse\', o Hand position "Mrigi mudra": It consists of flexing the index and ring fingers of the hand, o Breathing: Gently close the right nostril with the thumb, inhale fingers and exhale slowly through the right. Keeping your right nostril open, inhale, close it, and slowly open and exhale through the left. This is a cycle. Repeat 3-5 times and then release the hand mudra and return to normal breathing.

yoga exercise

tai chi exercises OTHER

the patients will receive tai chi in the form of Commencing form, Repulse Monkey,Grasp Peacock's Tail,Move Hands like Moving Clouds (left side only), Fair Lady Works at Shuttles, Golden Cock Stands on One Leg (left and right),Brush Knees and Twist Steps, Closing form.

tai chi exercises

tradional physical therapy OTHER

Patients will receive traditional physiotherapy breathing, massage and relaxation exercises

Pilates exercises; tai chi exercises; traditional physical therapy; yoga exercise

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• A score of 3.5 or less on the Expanded Disability Status Scale (EDSS) because individuals with an EDSS score greater than 3.5 need more assistance, being less independent (Zorina et al.,2020).
• All patients are taking their conventional medical treatment of relapsing-remitting stage
• Age over than 18 years
• All definite multiple sclerosis patients diagnosed as MS according to revised McDonald criteria 2017 .
• Both males and females will be included
• All Patients will be referred from neurologist.

You may not qualify if:

• Patients will be excluded if their diagnosis is not clearly established, if they suffer from an acute relapse or severe cognitive deficits, or have signs of any psychiatric disease -Brain surgery/trauma/history of brain disease (stroke), other independent neurological history
• Rheumatic diseases and other acute or chronic inflammations
• Vascular disease, spinal cord compression, vitamin B 12 deficiency
• Other conditions that affect the smooth progress of the inspection: such as hearing impairment, comprehension impairment, poor compliance
• Alcoholism or drug dependence (addiction)
• Pregnancy

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Multiple Sclerosis

Interventions

Exercise Movement Techniques

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Intervention Hierarchy (Ancestors)

Physical Therapy Modalities; Therapeutics

Central Study Contacts

Alshaymaa s Abd el-azeim, phd

CONTACT

01033771553; alshaymaa.shaaban@pt.cu.edu.eg

nabil M Abd Al aaL, Phd

CONTACT

01200133613; nabil.mahmoud@cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: opaque sealed envelope
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator: alshaymaa shaaban abd el azeim

Model Details: pilates, yoga, tai chi and traditional therapy

Study Record Dates

• First Submitted: September 21, 2024
• First Posted: September 25, 2024
• Study Start: October 10, 2024
• Primary Completion: July 30, 2025
• Study Completion: July 30, 2025
• Last Updated: September 25, 2024

Record last verified: 2024-09