Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
Split Face Comparative Study of Stromal Vascular Fraction Enriched PRP Versus Each Alone in Treatment of Atrophic Post-acne Scars
1 other identifier
interventional
30
1 country
1
Brief Summary
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt side treated with PRP, lt side treated with SVF
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Dec 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 6, 2023
CompletedFirst Posted
Study publicly available on registry
July 29, 2024
CompletedStudy Start
First participant enrolled
December 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2026
CompletedJuly 29, 2024
July 1, 2024
1 year
October 6, 2023
July 24, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
change in severity of acne scars using Goodman scoring system
at baseline, acne scars will be assessed clinically using the 4 point grading system proposed by Goodman \&colleagues in 2006, patients' complaints and expectations will be addressed as well and the impact of acne scars on patients' quality of life will be investigated using the dermatology life quality index (DLQI). Goodman scoring system will be used at the last session and at the follow up visit to measure the change pre and post treatment.
3 monthly sessions and follow up for 3 months after the last visit
Study Arms (3)
SVF enriched PRP vs PRP
EXPERIMENTALSVF enriched PRP vs SVF
ACTIVE COMPARATORPRP vs SVF
ACTIVE COMPARATORInterventions
Adipose derived stromal vascular fraction cells will be aspirated and isolated from patient autologous adipose tissue and used to enrich patient's autologous platelet rich plasma then will be used to treat atrophic post acne scars versus each alone.
Eligibility Criteria
You may qualify if:
- patients with atrophic post acne scars without any previous treatment trials.
- adequate blood picture, no anemia, no bleeding or platelet disorders.
You may not qualify if:
- pregnant and lactating females.
- elderly.
- patients with bleeding tendencies.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Zagazig University Hospitals
Zagazig, Egypt
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dermatology assistant professor
Study Record Dates
First Submitted
October 6, 2023
First Posted
July 29, 2024
Study Start
December 1, 2024
Primary Completion
December 1, 2025
Study Completion
February 1, 2026
Last Updated
July 29, 2024
Record last verified: 2024-07