Analysis of Postoperative Analgesic of Different Nerve Blocks for Total Knee Replacement Surgery

NCT06521619 | Completed

• 1 other identifier: FJUH113365
• Study Type: observational
• Target: 126
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a retrospective analysis using the accumulated clinical database from 2017/09-2023/12 to analyze patients who underwent total knee arthroplasty and received nerve blocks. The aim is to compare the analgesic effects, incidence of nerve injury, and rate of chronic pain under different nerve block techniques.

Conditions

Pain; Total Knee Replacement; Motor Function

Keywords

Analgesia; Nerve block; Total knee replacement

Outcome Measures

Primary Outcomes (1)

• Acute postoperative pain

  Acute postoperative pain

  Up to two days after surgery

Secondary Outcomes (3)

• Range of motion

  Up to two days after surgery

• Analgesic consumption

  Up to two days after surgery

• Ambulation time

  Up to two days after surgery

Study Arms (2)

Patient receiving Sciatic and Femoral nerve blocks

Patient receiving Sciatic and Femoral nerve blocks

Procedure: Femoral and sciatic nerve blocks

Patient receiving Adductor canal block and infiltration of posterior capsule of knee

Patient receiving Adductor canal block and infiltration of posterior capsule of knee

Interventions

Femoral and sciatic nerve blocks PROCEDURE

Patients receiving Adductor canal block and infiltration of posterior capsule of knee

Also known as: Adductor canal block and infiltration of posterior capsule of knee

Patient receiving Sciatic and Femoral nerve blocks

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Inclusion Criteria: * Patient receiving general anesthesia combined with nerve blocks for total knee replacement

You may qualify if:

• Patient receiving general anesthesia combined with nerve blocks for total knee replacement

You may not qualify if:

• Age less than 20 years old
• Not receiving nerve blocks
• American society of anesthesiologist physical status class greater than 4
• Contraindicated to receiving nerve blocks

Sponsors & Collaborators

• Fu Jen Catholic University Hospital: lead

Study Sites (1)

Fu Jen Catholic University Hospital

New Taipei City, 24300, Taiwan

Location

Related Publications (1)

• Sung CH, Liu JH, Hung CF, Fu CH. Comparative analysis of adductor canal block combined with iPACK block versus femoral combined with sciatic nerve blocks: a propensity score matched study. BMC Anesthesiol. 2025 May 16;25(1):249. doi: 10.1186/s12871-025-03112-z.

  PMID: 40380131 DERIVED

MeSH Terms

Conditions

Pain; Agnosia

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Perceptual Disorders; Neurobehavioral Manifestations; Nervous System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Attending anesthesiologists

Study Record Dates

• First Submitted: July 22, 2024
• First Posted: July 26, 2024
• Study Start: June 26, 2024
• Primary Completion: July 31, 2024
• Study Completion: July 31, 2024
• Last Updated: February 17, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)