NCT07275983

Brief Summary

Intraoperative anesthetic management for total knee replacement (TKR) can be performed under general or spinal anesthesia. These two techniques have their own characteristics and may impact postoperative recovery differently. However, there are no studies in the literature analyzing postoperative functional recovery after TKR surgery according to the type of anesthesia. The objective of this study is to compare postoperative recovery, assessed by the QoR-15F score, in patients undergoing TKR under spinal anesthesia versus surgery under general anesthesia.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 3, 2024

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

March 28, 2025

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 3, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 3, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

December 10, 2025

Completed
Last Updated

December 10, 2025

Status Verified

March 1, 2025

Enrollment Period

1.6 years

First QC Date

March 28, 2025

Last Update Submit

December 8, 2025

Conditions

Total Knee Replacement

Keywords

kneeTotal Knee ReplacementSpinal Anesthesia

Outcome Measures

Primary Outcomes (1)

  • QoR-15F score

    at Day 1, Day3, Day 14, and Day 28 postoperatively

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult subject having total knee replacement surgery between January 1, 2020 and June 30, 2023

You may qualify if:

  • Male or female, 18 years of age or older (no upper age limit)
  • Underwent total knee replacement surgery between January 1, 2020 and June 30, 2023
  • Assessed using the QoR-15F score

You may not qualify if:

  • Subject (and/or their legal representative, if applicable) who expressed their opposition to the reuse of their data for scientific research purposes.
  • Revision, emergency, oncological, bilateral, or septic surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Service d'Anesthésiologie - Réanimation Chirurgicale - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

Central Study Contacts

Eric NOLL, MD, PhD

CONTACT

33 3 88 12 70 76eric.noll@chru-strasbourg.fr

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 28, 2025

First Posted

December 10, 2025

Study Start

May 3, 2024

Primary Completion

December 3, 2025

Study Completion

December 3, 2025

Last Updated

December 10, 2025

Record last verified: 2025-03

Locations

FR(1)