Comparison of the Effectiveness of Sambiloto Herbs (Andrographis Paniculata) and Brisk Walking Exercise on Blood Pressure of Obese Patients

NCT06520527 | Not Yet Recruiting DMC

• 1 other identifier: 2504031945
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Problem Formulation

1. 1.Is there an effect of giving jamu sambiloto (Andrographis paniculata) on blood pressure in obese people in Jekan Raya District?
2. 2.Is there an effect of brisk walking exercise on blood pressure in obese people in Jekan Raya District?
3. 3.Is there an effect of brisk walking exercise and combined administration of jamu sambiloto (Andrographis paniculata) on blood pressure in obese people in Jekan Raya District?
4. 4.Is there a difference in effectiveness between the administration of jamu sambiloto (Andrographis paniculata) and brisk walking exercise and the combination on blood pressure in obese people in Jekan Raya District?
5. 5.Knowing the effect on blood pressure of obese people in Jekan Raya District before and after giving Jamu Sambiloto (Andrographis paniculata).
6. 6.Knowing the effect on blood pressure of obese people in Jekan Raya District before and after doing Brisk Walking Exercise.
7. 7.Knowing the effect before and after giving Jamu Sambiloto (Andrographis paniculata) and Brisk Walking Exercise on Blood Pressure in obese people in Jekan Raya District.

Conditions

MeSH

Keywords

Obese

Outcome Measures

Primary Outcomes (1)

• Systole and Diastole Differences

  Difference in Systole and Diastole before and after treatment

  7 consecutive days

Study Arms (5)

Brisk Walking Exercise

EXPERIMENTAL

Moderate activity that uses brisk walking techniques for 30 minutes at an average speed of up to 5 km/h or 100 steps per minute.a

Behavioral: Brisk Walking Exercise

Andrographis Paniculata

EXPERIMENTAL

Jamu Sambiloto is herbal medicine obtained through products that already have a distribution permit and have a distribution permit registration number, with a consumption dose of 1 capul / day or 350 grams for 7 consecutive days.

Dietary Supplement: Andrographis paniculata

Combination

EXPERIMENTAL

Moderate activity that uses brisk walking techniques for 30 minutes at an average speed of up to 5 km/h or 100 steps per minute.a Jamu Sambiloto is herbal medicine obtained through products that already have a distribution permit and have a distribution permit registration number, with a consumption dose of 1 capul / day or 350 grams for 7 consecutive days.

Other: Combination

Control

NO INTERVENTION

Obese with no intervention

Normal

NO INTERVENTION

Normal with no intervention

Interventions

Andrographis paniculata DIETARY_SUPPLEMENT

Jamu Sambiloto is herbal medicine obtained through products that already have a distribution permit and have a distribution permit registration number, with a consumption dose of 1 capul / day or 350 grams for 7 consecutive days.

Andrographis Paniculata

Brisk Walking Exercise BEHAVIORAL

Moderate activity that uses brisk walking techniques for 30 minutes at an average speed of up to 5 km/h or 100 steps per minute.

Brisk Walking Exercise

Combination OTHER

Moderate activity that uses brisk walking techniques for 30 minutes at an average speed of up to 5 km/h or 100 steps per minute. Jamu Sambiloto is herbal medicine obtained through products that already have a distribution permit and have a distribution permit registration number, with a consumption dose of 1 capul / day or 350 grams for 7 consecutive days.

Combination

Eligibility Criteria

• Age: 19 Years - 39 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Body Mass Index (BMI) ≥ 25 kg/m2 (Obesity 1) Blood pressure does not exceed 139/89 mmHg (High Normal) Adult age (19-39 years) Willing to be a respondent with informed consent Have health insurance coverage

You may not qualify if:

• Not in place or out of town during the study Experiencing illness that cannot carry out research interventions and data collection Resign during the study Routine exercise (Exercise every day less than 6000 steps). Taking anti-hypertensive drugs regularly Pregnant and breastfeeding mothers Routinely consume jamu sambiloto History of bone and joint disease that prevents physical activity History of cardiovascular or kidney disease

Sponsors & Collaborators

• Universitas Palangka Raya: lead

Study Sites (1)

Sports Facilities

Palangkaraya, Central Kalimantan, 73111, Indonesia

Location

MeSH Terms

Conditions

Obesity

Interventions

Andrographis paniculata extract

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Muhammad Revo Andaluzio Sazly Revo Sazly

CONTACT

+6281808154654; revosazly1@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Agnes Veronica Agustin

Study Record Dates

• First Submitted: July 21, 2024
• First Posted: July 25, 2024
• Study Start: July 21, 2024
• Primary Completion: August 1, 2024
• Study Completion: September 1, 2024
• Last Updated: July 25, 2024

Record last verified: 2024-07

Locations

ID (1)