The Effect of Salt Water Nebulization on Cough, Sputum and Quality of Life in Chronic Obstructive Pulmonary Patients

NCT06519188 | Completed

• 1 other identifier: Salt Water Nebulization
• Study Type: interventional
• Target: 81
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this clinical trial is to evaluate the effects of salt-water nebulization on individuals with chronic obstructive pulmonary disease. The main questions it aims to answer are: Does salt-water application have an effect on cough and sputum management in individuals with COPD diagnosis? Does salt-water application have an effect on dyspnea management in individuals with COPD diagnosis? Does salt-water application have an effect on the quality of life in individuals with COPD diagnosis? The work was continued with two groups that did and did not practice. The group who made the application made the application twice a day every day for 2 months. The results of both groups were compared.

Conditions

Copd

Keywords

quality of life; cough; dyspnea; COPD; saline water; nursing

Outcome Measures

Primary Outcomes (2)

• The effect of salt water application on cough in individuals diagnosed with COPD after a 8 weeks period.

  COPD Assesment Test's 1st question is belong to cough. The cough assessment of the patients was evaluated from "0" (no cough) to "5" (a lot of coughing). As the score obtained from the scale increases, the rate of being affected by COPD also increases.

  Base week and measurement interval is 8 weeks.

• The effect of salt water application on sputum management in individuals diagnosed with COPD after a 8 weeks period.

  COPD Assesment Test's 2nd question is belong to sputum. The sputum assessment of the patients was evaluated from "0" (no sputum) to "5" (a lot of sputum). As the score obtained from the scale increases, the rate of being affected by COPD also increases.

  Base week and measurement interval is 8 weeks.

Secondary Outcomes (2)

• The effect of salt water application on dyspnea management in individuals diagnosed with COPD after a 8 weeks period.

  Base week and measurement interval is 8 weeks.

• The effect of salt water application on quality of life in individuals diagnosed with COPD after a 8 weeks period.

  Base week and measurement interval is 8 weeks.

Study Arms (2)

NEBUL APPLICATION GROUP

EXPERIMENTAL

The experimental group patients were taught the method of nebulization with 5 ml isotonic sodium chloride. Patients were asked to perform the application twice a day, in the morning and in the evening, for two months.

Other: Nebulization application with 5 ml isotonic sodium chloride

NON APLICATION GROUP

NO INTERVENTION

No intervention was performed on control group patients who volunteered for the study.

Interventions

Nebulization application with 5 ml isotonic sodium chloride OTHER

Nebulization application with 5 ml isotonic sodium chloride in the morning and evening for two months.

NEBUL APPLICATION GROUP

Eligibility Criteria

• Age: 35 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years and above,
• Volunteer to participate in the research,
• Diagnosed with Stable COPD by the physician,
• Those who have not had an attack in the last month (are stable in terms of drug treatment),
• Having no vision, speech or hearing problems that would prevent understanding and applying the information given,
• Those who have smoked for at least 10 years or more,
• Individuals who are mentally competent (without intellectual disability).

You may not qualify if:

• Those who do not want to participate in the research,
• Hearing-speech impaired,
• Unable to communicate due to speaking different languages,
• Patients diagnosed by a physician with hypertension, ischemic heart disease, congestive heart failure, atrial fibrillation, chronic renal failure, stroke and other cerebrovascular disease, angina, major psychiatric disease (dementia, schizophrenia, etc.).

Sponsors & Collaborators

• Ministry of Health, Turkey: lead

Study Sites (1)

Yedikule Chest Surgeory and Chest Disease Hospital

Istanbul, Zeytinburnu, 34020, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Cough; Dyspnea

Interventions

Sodium Chloride

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Chlorides; Hydrochloric Acid; Chlorine Compounds; Inorganic Chemicals; Sodium Compounds

Study Officials

• ZELIHA ERMIS

  MOH TURKEY

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head Investigator

Model Details: pretest, posttest randomized controlled trial

Study Record Dates

• First Submitted: June 30, 2024
• First Posted: July 25, 2024
• Study Start: February 28, 2022
• Primary Completion: May 28, 2022
• Study Completion: December 30, 2022
• Last Updated: July 30, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)