Screening Tool for Malnutrition, Sarcopenia, and Cachexia

NCT06516367 | Completed

• 1 other identifier: Ain Shams Screening tools
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

There is an accumulating evidence of the overlap and frequent co-occurrence of twasting conditions in older adults. Those conditions include malnutrition, sarcopenia, and cachexia, Therefore , a tool capable of simultaneously screening for all three conditions is imperative. In this study, we developed and validated a new tool for the simultaneous screening of muscle wasting diseases in older adults. The diagnostic accuracy of the new tool was compared to other validated screening tools including the Mini Nutritional Assessment-Short Form (MNA-SF), the Short Nutritional Assessment Questionnaire (SNAQ), and the Simple Questionnaire to Rapidly Diagnose Sarcopenia (SARC-F).

Conditions

Malnutrition; Sarcopenia; Cachexia

Keywords

screening; older adult; malnutrition; cachexia; sarcopenia

Outcome Measures

Primary Outcomes (2)

• reliability of a new tool for the simultaneous screening of muscle wasting diseases in older adults

  Relaibility; Cronbach's alpha coefficient was used to evaluate the internal consistency.

  10 months

• validity of a new tool for the simultaneous screening of muscle wasting diseases in older adults

  Validity; Spearman's correlation coefficient was used to examine construct validity of the new tool

  10 months

Secondary Outcomes (1)

• The diagnostic accuracy of the new tool

  10 months

Interventions

Ain Shams University Screening Tool for Malnutrition, Sarcopenia, and Cachexia (ASUST-MSC) OTHER

25 items dichotomous questionnaire

Also known as: bioelectrical impedence analysis, handheld dynamometer

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

300 older participants aged 60 years old and above who were admitted to Ain Shams University Hospitals or interviewed at the hospital clinic

You may qualify if:

• Participants Aged 65 years and older, who agree to participate

You may not qualify if:

• Patients with critical illness.
• Patients with severe cognitive, hearing or visual impairment hindering proper communication
• Patients with physical disability that interfere with physical performance assessment or hand grip measurement
• Patient with any contraindication of to the use of BIA) e.g. presence of a pacemaker, other implanted electrical devices, or metal implants, volume overload

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, 11566, Egypt

Location

MeSH Terms

Conditions

Malnutrition; Sarcopenia; Cachexia

Condition Hierarchy (Ancestors)

Nutrition Disorders; Nutritional and Metabolic Diseases; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Weight Loss; Body Weight Changes; Body Weight; Thinness

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Geriatrics and Gerontology

Study Record Dates

• First Submitted: July 3, 2024
• First Posted: July 23, 2024
• Study Start: June 1, 2023
• Primary Completion: April 30, 2024
• Study Completion: April 30, 2024
• Last Updated: July 23, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)