A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation
1 other identifier
observational
700
1 country
1
Brief Summary
The goal of this observational study is to investigate the correlation between portal vein thrombosis (PVT) and the prognosis of liver transplantation. The main questions it aims to address are: What is the prevalence of PVT? What are the risk factors associated with PVT? What is the prognostic impact of preoperative PVT on liver transplantation? Participants are divided into two groups: the PVT group and the non-PVT group. The investigators will comparatively analyze the data of both groups, estimate the prevalence and risk factors of PVT, construct a predictive model for PVT that is applicable in clinical settings, and clarify the prognostic effects of PVT.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2016
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2016
CompletedFirst Submitted
Initial submission to the registry
July 8, 2024
CompletedFirst Posted
Study publicly available on registry
July 22, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2025
CompletedSeptember 18, 2025
September 1, 2025
10 years
July 8, 2024
September 15, 2025
Conditions
Outcome Measures
Primary Outcomes (3)
Death
Rate of death from various causes after liver transplant
10 years
Postoperative portal vein thrombosis
Number of participants with portal vein thrombosis after liver transplant
10 years
Postoperative portal vein stenosis
Number of participants with portal vein stenosis after liver transplant
10 years
Secondary Outcomes (1)
Postoperative complications
1 year
Study Arms (2)
PVT
Participants who meet the inclusion criteria for portal vein thrombosis prior to liver transplantation
non-PVT
Participants who meet the inclusion criteria for the absence of portal vein thrombosis prior to liver transplantation.
Interventions
Eligibility Criteria
Patients who underwent in situ liver transplantation at the Liver Transplantation Center of Beijing Friendship Hospital affiliated with Capital Medical University from 2016-1-1 to 2025-12-31
You may qualify if:
- Liver transplantation recipients
- Aged 18 years or older.
You may not qualify if:
- Retransplantation
- Multi-organ transplantation
- Portal vein tumor thrombus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Ru-zhou Cailead
Study Sites (1)
Beijing Friendship Hospital, Capital Medical University
Beijing, China
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- OTHER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
July 8, 2024
First Posted
July 22, 2024
Study Start
January 1, 2016
Primary Completion
December 31, 2025
Study Completion
December 31, 2025
Last Updated
September 18, 2025
Record last verified: 2025-09
Data Sharing
- IPD Sharing
- Will not share