Monetary Cost of Alzheimer's Disease in China

NCT02694445 | Completed Results DMC

• 1 other identifier: MAC-001
• Study Type: observational
• Target: 3,098
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to estimate the Chinese economic burden in patients with Alzheimer's Disease (AD).

Conditions

Alzheimer's Disease

Outcome Measures

Primary Outcomes (1)

• The Annual National Total Socioeconomic Cost for All AD Patients in China

  The annual national total socioeconomic cost for all patients with AD in China in 2015 was obtained, with the average annual cost per patient with AD from our results multiplied by the all number of patients with AD in 2015. So, the value reported in the data table below represents the total cost for all all participants in China.

  one year

Interventions

observation OTHER

The study is non-interventional.

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with Alzhemer's disease and their caregivers.

You may qualify if:

• New patients who are diagnosed with AD in this investigation or old patients who were diagnosed prior to this investigation were eligible；
• AD diagnosis must meet criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) and the National Institute of Neurologic and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA). The diagnosis should also meet the following: Modified Hachinski Ischemic Scale (MHIS) score≤4, Activity of Daily Living Scale (ADL) score≥23, Geriatric Depression Scale (GDS) score\<11. Neuroimaging MRI support AD diagnosis (exist atrophy in medial temporal lobe, white matter lesions score≤2 minutes according to the Fazekas criteria. AD disease classification according to mini-mental state examination (MMSE) scale (for illiterate dementia: mild: 21\~24 points; moderate: 11\~20 points; severe: 10 points or less; for lettered dementia: mild: 16\~19 points; moderate: 8\~15 points; severe: 7 points or less). The diagnosis of AD was confirmed by brain CT or MRI scans and by laboratory tests to rule out any other significant comorbidity.
• year-old and above, men or women.
• Normal vision or corrected visual, normal audition or corrected auditory, and cooperate with inspections and treatments.
• Consent to participate with a signed informed consent by himself/herself or guardians.

You may not qualify if:

• Patient with vascular dementia or dementia caused by other reasons, such as major depression or other major psychiatric illnesses, thyroid dysfunction, encephalitis, multiple sclerosis, and other dementia which includes frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), and Parkinson's dementia (PDD).
• MRI and laboratory tests (blood cell counts, liver and renal function, electrolyte, vitamin B12/folic, HIV, syphilis, and so on) do not support or rule out AD diagnoses.
• Has a history of alcoholism and drug abuse.

Sponsors & Collaborators

• Beijing Friendship Hospital: lead
• Chinese Medical Doctor Association: collaborator

Study Sites (1)

Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, 100053, China

Location

Related Publications (1)

• Li F, Chen S, Wei C, Jia J. Monetary costs of Alzheimer's disease in China: protocol for a cluster-randomised observational study. BMC Neurol. 2017 Jan 25;17(1):15. doi: 10.1186/s12883-017-0802-9.

  PMID: 28122529 DERIVED

MeSH Terms

Conditions

Alzheimer Disease

Interventions

Observation

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Results Point of Contact

• Title: Jianping Jia
• Organization: Department of Neurology, Xuan Wu Hospital,Beijing,China

jiajp@vip.126.com

010-63150669

Study Officials

• Jia Jianping, Doctor

  Head of Neurology Department, Capital Medical University

  STUDY CHAIR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 24, 2016
• First Posted: February 29, 2016
• Study Start: October 1, 2015
• Primary Completion: March 1, 2016
• Study Completion: May 1, 2016
• Last Updated: May 12, 2020
• Results First Posted: May 12, 2020

Record last verified: 2020-05

Locations

CN (1)