Preliminary Research Using Artificial Intelligence Technology to Identify Differences in Facial Expressions Between Healthy People, Patients With Cognitive Decline, and Patients With Dementia

NCT06513403 | Recruiting

• 1 other identifier: 202405102RIN
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Through artificial intelligence technology, we have conducted a preliminary study aimed at identifying differences in facial expressions among healthy individuals, patients with cognitive decline, and dementia patients. This research offers a novel method and tool for dementia screening, contributing to effective strategies for dementia prevention in our country. By utilizing this approach, we can effectively delay the onset of disability, promote healthy aging among our elderly population, reduce the caregiving burden on individuals, families, and society, and lower medical expenses.

Conditions

Artificial Intelligence Technology; Cognitive Decline; Dementia; Identify; Facial Expressions

Keywords

artificial intelligence technology; cognitive decline; dementia

Outcome Measures

Primary Outcomes (1)

• Facial Expression Test

  (A) Participants will sit in front of a computer screen and watch videos depicting positive (happy) or negative (sad) emotional stimuli. Each video will be less than 60 seconds long. (B) Participants will undergo the memory recall and calculation ability tests included in the MMSE. (C) While participants are undergoing the tests, video recording equipment will be used to observe and record the facial expression responses of the three groups.

  2024/8/1-2025/10/31

Eligibility Criteria

• Age: 50 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

* Normal cognition group (Health): 20 participants * Mild cognitive impairment group (MCI): 20 participants * Dementia group: 20 participants

You may qualify if:

• Age between 50 and 75 years.
• Experimental group:
• MCI group: CDR score of 0.5 or MMSE score between 20-25 (mild/early stage).
• Dementia group: CDR score greater than 1 or MMSE score between 10-19 (moderate/middle stage).
• Control group:
• Health group: MMSE score of 26 or above.
• Participants must be conscious and able to follow instructions.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

NTUH

Hsinchu, 300, Taiwan

RECRUITING

MeSH Terms

Conditions

Cognitive Dysfunction; Dementia; Facial Expression

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Nonverbal Communication; Communication; Behavior

Central Study Contacts

Yang Jung-Cheng

CONTACT

035326151; G68010@hch.gov.tw

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 17, 2024
• First Posted: July 22, 2024
• Study Start: September 1, 2024
• Primary Completion: August 31, 2025
• Study Completion: October 31, 2025
• Last Updated: April 15, 2025

Record last verified: 2024-07

Locations

TW (1)