NCT06503341

Brief Summary

More research is needed to articulate the most effective ways to use these tools as screening tests in cardiovascular risk assessments and how they ultimately affect CVD mortality and morbidity outcomes. Clinicians are encouraged to continue sharing decision-making with patients to combine their unique cardiovascular risk factors and develop a comprehensive, effective treatment plan.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
183mo left

Started Jun 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress24%
Jun 2021Jun 2041

Study Start

First participant enrolled

June 17, 2021

Completed
3.1 years until next milestone

First Submitted

Initial submission to the registry

July 9, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 16, 2024

Completed
6.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2031

Expected
10 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2041

Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

10 years

First QC Date

July 9, 2024

Last Update Submit

April 9, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • cardiovascular risk assesesment

    risk stratification of Cardiovascular diseases (CVD) in patients without established CVD but with CVD co morbids.we are using Atherosclerotic Cardiovascular Diseases (ASCVD) Risk Score and World Heart Organization(WHO) Risk Score for CVD Risk Assesment. In ASCVD Risk Score, we categorize population into low risk ( score \<5), borderline(score between 5 and 7.4) ,intermediate( score between 7.5 an 19.9) and high risk (score\>20), using all parameters for risk assesment. For WHO risk score calculation we are using WHO Risk score system for South Asia. https://cdn.who.int/media/docs/default-source/cardiovascular-diseases/south-asia.pdf?sfvrsn=c5b0d9a3\_2

    Ten years

Secondary Outcomes (2)

  • Cardiovascular risk reduction

    Ten years

  • Cardiovascular related deaths

    Ten years.

Study Arms (1)

Adult patients

Adult patients with or without cardiovascular diseases.

Other: Cardiovascular risk assesment

Interventions

ASCVD Score and WHO Cardiovascular Risk score.

Adult patients

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Both genders, age 18 and above, visiting preventive cardiology clinics with or without established CVD and may or may not have CVD risk factors.

You may qualify if:

  • All individuals attending the preventive cardiology clinics.

You may not qualify if:

  • Individuals who refused to give consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Institute of Cardiovascular Diseases

Karachi, Sindh, 75510, Pakistan

RECRUITING

Related Publications (1)

  • Rauf R, Khan MN, Sial JA, Qamar N, Saghir T, Kazmi KA. Primary prevention of cardiovascular diseases among women in a South Asian population: a descriptive study of modifiable risk factors. BMJ Open. 2024 Nov 14;14(11):e089149. doi: 10.1136/bmjopen-2024-089149.

Study Officials

  • Dr Rubina Rauf

    National Institute of Cardiovascular Diseases

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
10 Years
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor Preventive Cardiology

Study Record Dates

First Submitted

July 9, 2024

First Posted

July 16, 2024

Study Start

June 17, 2021

Primary Completion (Estimated)

June 1, 2031

Study Completion (Estimated)

June 1, 2041

Last Updated

April 13, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations