Prognostic Significance of Preoperative Nutritional Status on Postoperative Acute Kidney Injury

NCT06496802 | Not Yet Recruiting

• 1 other identifier: 101662
• Study Type: observational
• Target: 1,880
• Locations: 0 countries
• Sites: N/A

Brief Summary

The incidence of postoperative acute kidney injury (AKI) is high in patients undergoing lung resection surgery, especially in the elderly. Early identification of high-risk postoperative AKI patients can help develop prevention and treatment management strategies.

Conditions

Acute Kidney Injury; Pneumonectomy

Keywords

Acute Kidney Injury; lung resection surgery; malnutrition; prediction model

Outcome Measures

Primary Outcomes (1)

• Postoperative acute kidney injury

  In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.

  Within 7 days after surgery

Interventions

no intervention OTHER

no intervention

Eligibility Criteria

• Age: 65 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Older patients (aged ≥ 65 years) who underwent lung resection surgery under general anesthesia at our Hospital between January 2020 and June 2024 were included in our study. Lung resection surgery included pneumonectomy , bilobectomy , lobectomy, segmentectomy, wedge resection/bullectomy.

You may qualify if:

• aged ≥ 65 years
• lung resection surgery including：pneumonectomy , bilobectomy , lobectomy, segmentectomy, wedge resection/bullectomy.

You may not qualify if:

• patients with an American Society of Anesthesiologists (ASA) physical status V.
• those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis).
• those did not have sufficient data required for nutritional evaluation or AKI evaluation.

Sponsors & Collaborators

• Wanmin Liao: lead

MeSH Terms

Conditions

Acute Kidney Injury; Malnutrition

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Nutrition Disorders; Nutritional and Metabolic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 4, 2024
• First Posted: July 11, 2024
• Study Start: July 1, 2024
• Primary Completion: September 15, 2024
• Study Completion: September 15, 2024
• Last Updated: July 11, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share