Predicting CSA-AKI With ACTA-PORT Score

NCT06484907 | Completed

• 1 other identifier: ABCH-AR-CAY-01
• Study Type: observational
• Target: 467
• Locations: 1 country
• Sites: 1

Brief Summary

In the scope of this study, it will be determined whether the ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) scoring system can predict the incidence of events in other organ systems, and the feasibility of conducting multiple assessments using a single simple score will be investigated.

Conditions

Cardiac Disease; Blood Transfusion; Acute Kidney Injury

Keywords

Cardiopulmonary Bypass; Cardiac Surgery; Transfusion; Acute Kidney Injury; ACTA PORT

Outcome Measures

Primary Outcomes (1)

• KDIGO AKI Staging

  KDIGO is in the process of developing the Clinical Practice Guideline for Acute Kidney Injury (AKI) and Acute Kidney Disease (AKD). ///// Stage 1: Serum creatinine 1.5-1.9 times baseline or ≥0.3 mg/dl (≥26.5 mmol/l) increase or Urine output \<0.5 ml/kg/h for 6-12 hours ////// Stage 2: Serum creatinine 2.0-2.9 times baseline or \<0.5 ml/kg/h for ≥12 hours /////// Stage 3: Serum creatinine 3.0 times baseline or Increase in serum creatinine to ≥4.0 mg/dl (≥353.6 mmol/l) or Initiation of renal replacement therapy or in patients \<18 years, decrease in eGFR to \<35 ml/min per 1.73 m² or Urine output \<0.3 ml/kg/h for ≥24 hours or anuria for ≥12 hours

  Preoperative (last week before operation) and daily after the operation for 7 days

Secondary Outcomes (6)

• Mechanical Ventilation Duration

  the duration after surgery up to a month

• Intensive Care Duration

  the duration after surgery up to a month

• Hospital Stay Duration

  the duration after surgery up to a month

• Mortality

  the duration after surgery up to a month

• Complications

  the duration after surgery up to a month

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients having open heart surgery by using cardiopulmonary bypass pump in Ankara Bilkent City Hospital between 01 July 2024 - 01 November 2024.

You may qualify if:

• Patients over 18 years old
• Patients having open heart surgery
• Patients undergoing surgery by using cardiopulmonary bypass pump

You may not qualify if:

• Patients under 18 years old
• Patients diagnosed with kidney disease

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara Bilkent City Hospital

Ankara, Ankara, 06800, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Heart Diseases; Acute Kidney Injury

Condition Hierarchy (Ancestors)

Cardiovascular Diseases; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• Zeliha Asli DEMIR, Ph.D

  Ankara City Hospital Bilkent

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Doctor

Study Record Dates

• First Submitted: June 25, 2024
• First Posted: July 3, 2024
• Study Start: July 1, 2024
• Primary Completion: September 15, 2024
• Study Completion: December 1, 2024
• Last Updated: June 26, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)