A Predictive Model for Recurrent Acute Pancreatitis
Construction and Validation of an Early Prediction Nomogram for Recurrent Acute Pancreatitis Based on the MIMIC Database
1 other identifier
observational
659
0 countries
N/A
Brief Summary
The goal of this observational study is to learn about recurrent acute pancreatitis (RAP) .The main questions it aims to answer are:
- 1.What are the risk factors for RAP?
- 2.How to predict RAP?
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2016
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2018
CompletedFirst Submitted
Initial submission to the registry
June 13, 2024
CompletedFirst Posted
Study publicly available on registry
June 18, 2024
CompletedJune 24, 2024
June 1, 2024
2 years
June 13, 2024
June 18, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number of Participants Who Experience Recurrent Acute Pancreatitis
Recurrent acute pancreatitis was defined as two or more confirmed episodes of acute pancreatitis, excluding chronic pancreatitis, with an interval of more than 3 months between attacks, and complete resolution of symptoms during the inter-episodic periods.
From admission to 3 years after discharge.
Study Arms (2)
Recurrent acute pancreatitis
Non-recurrent acute pancreatitis
Eligibility Criteria
We collected data from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database and from patients with acute pancreatitis in the Department of Gastroenterology of Clinical Medical College of Yangzhou University between January 2016 and December 2017, forming the primary and validation cohort, respectively.
You may qualify if:
- Meeting the diagnostic criteria of acute pancreatitis (AP)
- Age ≥18 years
- Systematic examination and diagnostic information were available after admission
You may not qualify if:
- Not the first episode of AP
- The duration of hospital stay was less than 24 hours
- Died within the first episode of AP
- A history of chronic pancreatitis or tumor
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Qinghao Wanglead
Related Publications (2)
Johnson AEW, Bulgarelli L, Shen L, Gayles A, Shammout A, Horng S, Pollard TJ, Hao S, Moody B, Gow B, Lehman LH, Celi LA, Mark RG. MIMIC-IV, a freely accessible electronic health record dataset. Sci Data. 2023 Jan 3;10(1):1. doi: 10.1038/s41597-022-01899-x.
PMID: 36596836BACKGROUNDBanks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS; Acute Pancreatitis Classification Working Group. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013 Jan;62(1):102-11. doi: 10.1136/gutjnl-2012-302779. Epub 2012 Oct 25.
PMID: 23100216BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Master of Medicine
Study Record Dates
First Submitted
June 13, 2024
First Posted
June 18, 2024
Study Start
January 1, 2016
Primary Completion
December 31, 2017
Study Completion
June 30, 2018
Last Updated
June 24, 2024
Record last verified: 2024-06