Searching the Best Prognostic Factor in Out Come Evaluation in Patients With Acute Pancreatitis Admitted at Assiut University Hospitals

NCT03259880 | Unknown

• 1 other identifier: assiut university 7001
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Acute pancreatitis (AP) is rapid-onset inflammation of the pancreas that varies in severity from a self-limiting mild illness to rapidly progressive multiple organ failure. Statistics suggest that 10-20% of patients with AP develop severe AP (SAP),1 which usually has an unfavourable disease progression and is associated with a poor prognosis. The two most common and important causes of acute pancreatitis are gallstones (40-70%) and alcohol (25-35%) Gallstone pancreatitis is usually due to an obstructing stone in the pancreatic duct near the sphincter of Oddi . In alcohol-related pancreatitis, it is believed that the acinar cells of the pancreas are susceptible to damage by ethanol and underlie the etiology of the disease . Another common cause, iatrogenic pancreatitis, may occur after endoscopic retrograde cholangiopancreatography (ERCP) in up to 5% of patients. Other etiologies of acute pancreatitis include medications, infections, trauma, hereditary, hypertriglyceridemia and autoimmune disease.

Conditions

Acute Pancreatitis

Keywords

evaluation

Outcome Measures

Primary Outcomes (3)

• evaluation of the prognostic value of neutrophil _lymphocyte ratio in cbc in patients with acute pancreatitis admitted at assiut university hospitals.

  evaluation of the prognostic value neutrophil lymphocyte ratio in patient with acute pancreatitis

  one year

• evaluation of the prognostic value of LDH in patients with acute pancreatitis admitted at assiut university hospitals.

  evaluation of the prognostic value of LDH ratio in patient with acute pancreatitis

  one year

• evaluation of the prognostic value of urine analysis in patients with acute pancreatitis admitted at assiut university hospitals.

  evaluation of the prognostic value of urine analysis ratio in patient with acute pancreatitis

  one year

Eligibility Criteria

• Age: 16 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Evaluation of the best prognostic parameter in patients with acute pancreatitis

You may qualify if:

• patients with acute pancreatitis admitted at Assiut university hospital and the diagnosis of acute pancreatitis is confirmed if at least two of the following three features present:
• abdominal pain characteristic of acute pancreatitis.
• serum amylase and/or lipase greater than 3 times the upper limit of normal .
• radiographically demonstrated acute pancreatitis on CT scan or abdominal ultrasound.

You may not qualify if:

• Patients are excluded from the study if they do not meet the criteria for acute pancreatitis
• Patients who are under the age of 16.
• Patients with chronic pancreatitis.
• Patients with recurrent acute pancreatitis

Sponsors & Collaborators

• Fady Refaat Edwar Nasrallah: lead
• Assiut University: collaborator

MeSH Terms

Conditions

Pancreatitis

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: internal medicine resident,Assiut University hospital

Study Record Dates

• First Submitted: August 18, 2017
• First Posted: August 24, 2017
• Study Start: September 1, 2017
• Primary Completion: September 1, 2018
• Study Completion: September 1, 2018
• Last Updated: August 24, 2017

Record last verified: 2017-07