A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
A Clinical Study to Evaluate the Effectiveness of Casein Phosphopeptide, Amorphous Calcium Phosphate Paste (CPP-ACP) Used Alone or in Combination With Lasotronix (Diode Laser) to Treat Dentin Hypersensitivity
1 other identifier
interventional
120
1 country
1
Brief Summary
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects". DH has a prevalence rate ranging from 1.3% to 92.1%, commonly affecting old ages. The use of laser has opened new dimensions in the treatment of DH. To the author's knowledge, not much research work has been conducted using LASOTRONIX as a treatment modality with CPP-ACP. Therefore, this research aims to determine the effectiveness of Casein phospho peptide paste (CPP-ACP) used alone or combined with a diode laser (LASOTRONIX).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started May 2024
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 12, 2024
CompletedFirst Submitted
Initial submission to the registry
June 11, 2024
CompletedFirst Posted
Study publicly available on registry
June 18, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 10, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 10, 2024
CompletedJuly 26, 2024
July 1, 2024
3 months
June 11, 2024
July 25, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
treatment of dentin hypersensitivity
VAS Visual analogue scale will be used to determine the efficacy of different treatment methods.
0-3 moths
Study Arms (4)
Active Comparator
ACTIVE COMPARATORwould include patients (n=30) who will be given CPP-ACP paste application only
Experimental
EXPERIMENTALwould consist of patients (n=30) who will be given diode laser therapy only
Combination
OTHERwould include patients (n=30) who will be given a combination of CPP-ACP paste \& Laser therapy.
Control
OTHERwould be a control group
Interventions
This group will receive the combination of above two treatments
Eligibility Criteria
You may qualify if:
- Patients of either gender, with ages between 25-65 years
- should have at least more than one hypersensitive and vital tooth without any carious lesion or defective restoration
You may not qualify if:
- History of desensitizing therapy on the affected tooth/teeth in last six months (use of desensitizing toothpaste)
- use of antibiotics /analgesic/anti-inflammatory drugs
- history of smoking
- pregnancy
- those who are not willing to participate or give follow-ups
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Dr Sanam Faheem
Karachi, Sindh, 75330, Pakistan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Senior Lecturer
Study Record Dates
First Submitted
June 11, 2024
First Posted
June 18, 2024
Study Start
May 12, 2024
Primary Completion
August 10, 2024
Study Completion
October 10, 2024
Last Updated
July 26, 2024
Record last verified: 2024-07
Data Sharing
- IPD Sharing
- Will share