The Efficacy of Tele Rehabilitation- Based Task-Specific Training for Cognitive Function Improvement

NCT06428201 | Active Not Recruiting DMC

• 1 other identifier: MSRSW/Batch-Fall22/711
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

"This study investigates the feasibility of tele-rehabilitation combined with targeted training for cognitive enhancement in individuals with Multiple Sclerosis (MS). Multiple sclerosis (MS) is a chronic illness that affects the central nervous system, often resulting in cognitive impairments that significantly impact quality of life. Tele-restoration provides an accessible and effective method for delivering therapeutic interventions, particularly beneficial for those with mobility limitations.

Conditions

Sclerosis, Multiple

Outcome Measures

Primary Outcomes (1)

• Montreal Cognitive Assessment (MoCA) scale

  The MoCA scale is a comprehensive tool designed to evaluate various cognitive domains, including attention and concentration, executive functions, memory, language, visuospatial skills, conceptual thinking, calculations, and orientation. It provides a detailed assessment of cognitive performance, making it an ideal measure for tracking cognitive improvements in MS patients participating in the tele-rehabilitation and task-specific training programs.

  12 Months

Study Arms (2)

Control Group

ACTIVE COMPARATOR

Diagnostic Test: Control Group

EXP group

EXPERIMENTAL

Combination Product: Experimental Group

Interventions

Control Group DIAGNOSTIC_TEST

The control group receives standard care, which includes routine medical management and general physical rehabilitation exercises. This involves regular consultations with healthcare providers and exercises aimed at maintaining mobility and physical function. The control group also follows a schedule of three 45-minute sessions per week for 12 weeks, ensuring a consistent comparison with the experimental group.

Control Group

Experimental Group COMBINATION_PRODUCT

The experimental intervention involves tele-rehabilitation-based task-specific training to enhance cognitive functions in multiple sclerosis (MS) patients. This program includes cognitive exercises targeting memory, attention, executive function, and processing speed, conducted remotely via a tele-rehabilitation platform. Patients participate in three 45-minute sessions per week for 12 weeks. Each session is guided by a trained therapist, ensuring personalized support and real-time feedback.

EXP group

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Individuals with a diagnosis of MS confirmed by a neurologist.
• Between 18 and 65 years of age.
• Presence of psychosis confirmed by standardized psychometric testing.
• A stable treatment environment that allows intervention.
• Internet access with camera and computer/tablet.
• Ability to understand and follow course directions.
• Willingness to give informed consent.

You may not qualify if:

• Severe psychiatric co-morbidities affecting cognitive function.
• Concurrent intervention with other psychological rehabilitation programs.
• Lack of availability or use of technology necessary for tele-rehabilitation.
• Further research interventions.
• Unstable medical condition

Sponsors & Collaborators

• Superior University: lead

Study Sites (1)

District Head Quarters Hospital Narowal, Circular Road, Near Jassar Bypass, Narowal Location: Khalid Eye & Medical Care Block C Commercial Area, Jubilee Town, Lahore

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 20, 2024
• First Posted: May 24, 2024
• Study Start: September 1, 2023
• Primary Completion: April 1, 2024
• Study Completion: September 1, 2024
• Last Updated: May 24, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)