Electrophysiological Study of Berrettini Anastomosis

NCT06458751 | Completed

• 1 other identifier: MANOSENS
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The common opinion that sensory supply of digit 5 (D5) and medial half of digit 4 (D4) of the hand is by ulnar nerve, while the lateral half of D4 and the remaining digits is by median nerve is an oversimplification of a complex topic. Indeed, the literature demonstrated that both the median and ulnar nerves display a number of deviations to the traditionally taught branching patterns. The aim of our study was to investigate the physiological role of median and ulnar nerves in the sensory supply of D4.

Conditions

Electrophysiologic Study; Hand Anastomosis

Outcome Measures

Primary Outcomes (2)

• analysis of the sensory potential (UV amplitude in MSEC) recorded on both sides of the IV finger of the hand by stimulation of the median nerve and the ulnar one

  immediately after the procedure

• analysis of the sensory potential ( latency in MSEC) recorded on both sides of the IV finger of the hand by stimulation of the median nerve and the ulnar one

  immediately after the procedure

Study Arms (1)

30 healthy subjects with no history of neuromuscular disease

OTHER

30 healthy subjects with no history of previous neuromuscular disease and no abnormalities on neurological examination

Other: electrophysiological study; Device: electromyograph

Interventions

electrophysiological study OTHER

Antidromic sensory nerve conduction studies of median and ulnar nerves will be performed on both hands of 30 healthy subjects with no history of previous neuromuscular disease and no abnormalities on neurological examination., by using surface electrical stimulation at wrist and surface digital recording electrodes on both sides of D4.

30 healthy subjects with no history of neuromuscular disease

electromyograph DEVICE

surface electrical stimulation at wrist and surface digital recording electrodes on both sides of D4.

30 healthy subjects with no history of neuromuscular disease

Eligibility Criteria

• Age: 24 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• age 24-60 years
• male and female
• under informed consent
• no history of previous neuromuscular disease and no abnormalities on neurological examination

Sponsors & Collaborators

• Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico: lead

Study Sites (1)

Pediatric Emergency Department Clinica de Marchi, Foundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Milan, Italy

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: May 22, 2024
• First Posted: June 14, 2024
• Study Start: January 25, 2024
• Primary Completion: February 15, 2024
• Study Completion: March 15, 2024
• Last Updated: June 14, 2024

Record last verified: 2024-06

Locations

IT (1)