Effect of Soleus Muscle Push Ups on Oxidative Stress and Inflammatory Markers, Soleus Endurance, and Adipocytokines Between Type 2 Diabetic, Overweight/Obese and Normal Weight Individuals.
1 other identifier
interventional
72
0 countries
N/A
Brief Summary
The study aims to investigate the impact of Soleus Push Ups (SPU) on Soleus Muscle endurance, Oxidative Stress Markers, Inflammatory markers and Adipocytokines among people in the United Arab Emirates. This will be a pre-post intervention study with participants divided into three groups: Lean normal metabolic profile, metabolically healthy overweight/obese, and patients with Type 2 Diabetes Mellitus. Assessment of anthropometry and body composition, Soleus Muscle Endurance, blood tests for Inflammatory Markers, Oxidative Stress Markers, and Adipocytokines will be conducted pre and post-intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jun 2024
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 22, 2024
CompletedStudy Start
First participant enrolled
June 1, 2024
CompletedFirst Posted
Study publicly available on registry
June 10, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2024
CompletedJune 10, 2024
May 1, 2024
3 months
May 22, 2024
June 4, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Adipocytokine levels in the blood
Measured in μg/ml, using blood test by specialized personnel
3 months
Secondary Outcomes (1)
Soleus Muscle endurance through Heel Raise Test. • Inflammatory and Oxidative Stress markers through blood sample.
3 months
Other Outcomes (4)
BMI
3 months
Anthropometric data including weight, height and fat percentage
3 months
Physical Activity and Food habits
3 months
- +1 more other outcomes
Study Arms (2)
Interventional group
ACTIVE COMPARATORControl group
PLACEBO COMPARATORInterventions
Members will be asked to do the SPUs for 270 minutes/day for most days of the week (minimum 5 days) for 3 months: 1. Begin seated on a bench or chair so knees form a 90-degree angle with feet flat on the floor and toes pointed forward. Keep spine straight and shoulders back (not hunched or rounded forward). 2. Using a slow and controlled tempo, push toes into the floor and lift heels off the ground. 3. Hold for one to two seconds, pushing down on the balls of feet. Keep your thigh muscles relaxed. 4. Slowly lower heels and return to start. That's 1 rep. Without shoes Educational session will be given before the intervention time WhatsApp messages will be sent 1-2 times/day to remind the participants to continue doing the exercise and ascertain compliance. Also, the participants are required to daily fill logbook about the duration (in minutes) of the SPU that they did.
Eligibility Criteria
You may qualify if:
- Residents of UAE, both males and females
- Ages 20-50 years
- Uncomplicated Type 2 Diabetic on meds,
- Normal lean BMI
- Overweight and Obese
You may not qualify if:
- Recent orthopedic surgery in the LLs
- Pain in the LLs starting from Hips to Ankle.
- Presence of Varicose Veins in the LLs
- Present History of any cardiovascular condition
- Pregnant females
- Morbid Obesity
- Diabetics undergoing Insulin therapy only
- Smokers and alcohol consumption
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Instructor
Study Record Dates
First Submitted
May 22, 2024
First Posted
June 10, 2024
Study Start
June 1, 2024
Primary Completion
September 1, 2024
Study Completion
October 1, 2024
Last Updated
June 10, 2024
Record last verified: 2024-05
Data Sharing
- IPD Sharing
- Will share
In case of the need for further expansion of the research, the information might be shared with other researchers in the university without exposure of any personal information or names of participants.