Evaluation of Cardiopulmonary Parameters in Individuals With Asthma

NCT06449573 | Recruiting

• 1 other identifier: GO 23/533
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study compare the cardiopulmonary parameters of individuals with asthma with healthy subjects.

Conditions

Asthma

Outcome Measures

Primary Outcomes (1)

• Exercise capacity

  Exercise capacity will be assessed by Cardiopulmonary Exercise Test. The test will be performed on a bicycle ergometer. The test will be terminated when the target heart rate is reached or when the patient indicates that they are unable to continue the test. maximal oxygen consumption and the workload achieved will be recorded.

  20 minutes

Secondary Outcomes (5)

• Respiratory muscle strength

  8 minutes

• Peripheral muscle strength

  5 minutes

• Grip strength

  3 minutes

• Kinesiophobia

  3 minutes

• Quality of Life (symptoms, mood, activity limitation, environmental exposure)

  10 minutes

Study Arms (2)

Asthma

Inclusion Criteria: * Patients receiving step 5 asthma treatment * 18-65 years * Asthma under control (asthma control test ≥20) * No more than 2 exacerbations in the last 1 year Exclusion Criteria: * Non-consenting * Patients with asthma exacerbation requiring systemic steroid use for at least 3 days in the last 1 month * Being an active smoker

Other: Exercise capacity

Healthy Individuals

Inclusion Criteria: * No respiratory, cardiovascular and metabolic diseases * Regular non-smoker Exclusion Criteria: * Non-consenting * Pregnant women

Other: Exercise capacity

Interventions

Exercise capacity OTHER

cardiopulmonary exercise test used assessment of exercise capacity

Asthma; Healthy Individuals

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study will include asthma patients followed up by Hacettepe University Faculty of Medicine, Department of Chest Diseases, Immunology and Allergy Branch and healthy individuals.

You may qualify if:

• No respiratory, cardiovascular and metabolic diseases
• Regular non-smoker

You may not qualify if:

• Non-consenting
• Pregnant women

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University

Ankara, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Officials

• Naciye Vardar Yagli

  Hacettepe University

  STUDY DIRECTOR

• Melda Saglam

  Hacettepe University

  STUDY CHAIR

• Ebru Damadoglu

  Hacettepe University

  STUDY CHAIR

• Merve Firat

  Kirsehir Ahi Evran Universitesi

  STUDY CHAIR

• Aydan Aslı Aksel Uylar

  Hacettepe University

  PRINCIPAL INVESTIGATOR

• Melek Cihanbeylerden

  Hacettepe University

  STUDY CHAIR

Central Study Contacts

Aydan Aslı Aksel Uylar

CONTACT

+90312; aydanaaksel@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Study Record Dates

• First Submitted: March 3, 2024
• First Posted: June 10, 2024
• Study Start: March 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2025
• Last Updated: August 27, 2024

Record last verified: 2024-08

Locations

TU (1)