NCT07353242

Brief Summary

This study was designed as a pre-test-post-test randomized controlled experimental trial to determine the effects of buteyko breathing technique application on fatigue, exercise capacity, and asthma control in asthma patients.The study, planned as a randomized controlled experimental study, included a total of 90 participants. The sample consisted of asthma patients who applied to the Chest Diseases outpatient clinic of Gaziantep University Application and Research Hospital, had been diagnosed with asthma within the last 6 months, did not have heart failure, did not have communication or perception problems, did not have walking disabilities, and were between 18-59 years old.Following random assignment, participants were divided into two groups of 45 participants each. The groups were: 1) Buteyko 2) Control

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for not_applicable asthma

Timeline
Completed

Started Oct 2024

Shorter than P25 for not_applicable asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 15, 2024

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 25, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 25, 2025

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

January 13, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 20, 2026

Completed
Last Updated

January 20, 2026

Status Verified

January 1, 2026

Enrollment Period

8 months

First QC Date

January 13, 2026

Last Update Submit

January 13, 2026

Conditions

Keywords

Asthma,ButeykoFatigueBreathing ExercisesExercise CapacityAsthma Control

Outcome Measures

Primary Outcomes (1)

  • The Asthma Control Test (ACT)

    The Asthma Control Test (ACT) is a practical, patient-completed scale consisting of five questions, scored between 5 and 25 points, that assesses the level of asthma control; higher scores indicate better control.

    6 weeks

Secondary Outcomes (1)

  • The Chronic Obstructive Pulmonary Disease and Asthma Fatigue Scale (COPD)

    6 weeks

Study Arms (1)

Buteyko group

EXPERIMENTAL

In the Buteyko group, in addition to standard treatment, participants received training and practice in the Buteyko Breathing Technique aimed at reducing hyperventilation. The intervention was delivered as face-to-face group training by an internationally certified instructor and included a 30-minute theoretical session followed by practical exercises. These consisted of controlled breath-holding with reduced breathing performed while seated and walking, as well as a relaxation phase focusing on nasal breathing accompanied by calming music. Mouth taping was used throughout the exercises to promote nasal breathing. Participants were instructed to perform the exercises at home three times daily, with weekly outpatient follow-up visits, and were monitored for a total of six weeks.

Other: Buteyko Breathing Technique

Interventions

This intervention is distinguished by its standardized delivery by an internationally certified Buteyko practitioner and its integration of key Buteyko components, including reduced breathing, controlled breath-holding, nasal breathing with mouth taping, and relaxation. It incorporates both seated and walking-based exercises, uses objective measures such as Control Pause and step counting, and includes a structured home-based practice with weekly follow-up over six weeks.

Buteyko group

Eligibility Criteria

Age18 Years - 59 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Having been diagnosed with asthma within the last 6 months
  • Absence of heart failure
  • Absence of communication and perception problems
  • Absence of walking impairment Being between 18-59 years of age-

You may not qualify if:

  • Child patients
  • Those diagnosed with heart failure
  • Conditions that impede walking
  • Those with communication and perception problems

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gaziantep University

Gaziantep, Şehitkamil, 27000, Turkey (Türkiye)

Location

Related Publications (3)

  • Aluwı, M. F., Azmı, N. A., Zanudın, A., & Ramlı, A. (2025). Effect of Buteyko Breathing Technique and Inspiratory Muscle Training on Acute Exacerbation of Bronchial Asthma in a 55-Year-Old Patient: A Case Report. Buletin SK, 9(1), 55-60

    RESULT
  • AbdElmawla Elsaid, R. A., Zahran, W. E. K., & Elsaid Hafez, D. M. (2023). Comparison of the Effects of Buteyko and Diaphragmatic Breathing Technique on Improving Pulmonary Functions and Asthma Control among Patients with Bronchial Asthma. Egyptian Journal of Nursing and Health Sciences, 4(3), 58-76.

    RESULT
  • Abd Allah Abd El Hafeez, N., Khalil Hafez, M., Mohamed Ahmed, Z., Metwally El-Sayed, M., Abdelwahab Khedr, M., & Fathy Ahmed Dawood, R. (2025). Evaluating the Effect of Buteyko Breathing Technique in Enhancing Asthma Control and Life Quality Among Asthma Patients: A Nursing-Led Quasi-Experimental Study. Egyptian Journal of Health Care, 16(1), 831-852.

    RESULT

MeSH Terms

Conditions

AsthmaFatigue

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Adile Neşe

    University of Gaziantep

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assos Prof.

Study Record Dates

First Submitted

January 13, 2026

First Posted

January 20, 2026

Study Start

October 15, 2024

Primary Completion

June 25, 2025

Study Completion

July 25, 2025

Last Updated

January 20, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations