Relationship of Muscular Agenesis: Thin Plantar and Palmar Long as a Biomarker of Injury and Performance Marker in the Lower Limb and Upper Limb Respectively

NCT06448832 | Not Yet Recruiting

• 1 other identifier: Muscular Agenesis Thin plantar
• Study Type: observational
• Target: 132
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates muscle agenesis, specifically the absence of the palmaris longus and plantaris muscles, and its effects on injury risk, strength, and performance. Muscle injuries are common in sports, and the presence or absence of certain muscles can impact biomechanics and injury susceptibility. The study involves 132 subjects, divided into those with and without muscle agenesis, assessing injuries with the Nordic and CMDQ questionnaires and measuring strength with dynamometers. Results aim to clarify the controversial impact of muscle agenesis on functional disability and performance adaptation in the scientific literature.

Conditions

Abnormality, Congenital

Keywords

muscle agenesis; thin plantar; force; injuries; musculoskeletal palmar long; performance

Outcome Measures

Primary Outcomes (1)

• Presence of injury

  Presence of injury related to the upper and lower limb.

  At the start of the study (at baseline, 0 week).

Secondary Outcomes (1)

• Strength

  At the start of the study (at baseline, 0 week)

Study Arms (2)

Agenesis Group

Subjects with the presence of muscular agenesis of the plantar muscle and palmaris longus.

Diagnostic Test: Ultrasound

Non-agenesis Group

Subjects without the presence of muscular agenesis of the plantar muscle and palmaris longus.

Diagnostic Test: Ultrasound

Interventions

Ultrasound DIAGNOSTIC_TEST

An ultrasound examination of the musculature of the plantar muscle and long palmar muscle is performed to determine their presence or absence.

Agenesis Group; Non-agenesis Group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

People with and without muscle agenesis.

You may qualify if:

• Individuals who lead a sedentary lifestyle or who are not used to doing physical training on a regular basis (more than 2 h/week).
• People between 18 and 80 years old.

You may not qualify if:

• Individuals with an ongoing oncological process.
• People with an active infectious process.
• Subjects with psychiatric disorders.
• Individuals with intellectual disorders that prevent understanding of the intervention.
• People with judicial incapacity.
• Patients diagnosed with fibromyalgia.
• Pregnancy or probability of pregnancy.
• Individuals with sensory impairments in the hand that prevent manual pressure.

Sponsors & Collaborators

• University of Seville: lead

Study Sites (1)

Campus Científico-Tecnológico UAH. Av. de León, 3A, Alcalá de Henares, Madrid

Alcalá de Henares, Madrid, 28804, Spain

Location

Related Publications (11)

• Balsalobre-Fernandez C, Glaister M, Lockey RA. The validity and reliability of an iPhone app for measuring vertical jump performance. J Sports Sci. 2015;33(15):1574-9. doi: 10.1080/02640414.2014.996184. Epub 2015 Jan 2.

  PMID: 25555023 BACKGROUND

• Ioannis D, Anastasios K, Konstantinos N, Lazaros K, Georgios N. Palmaris Longus Muscle's Prevalence in Different Nations and Interesting Anatomical Variations: Review of the Literature. J Clin Med Res. 2015 Nov;7(11):825-30. doi: 10.14740/jocmr2243w. Epub 2015 Sep 25.

  PMID: 26491493 BACKGROUND

• Vanhoenacker FM, Desimpel J, Mespreuve M, Tagliafico A. Accessory Muscles of the Extremities. Semin Musculoskelet Radiol. 2018 Jul;22(3):275-285. doi: 10.1055/s-0038-1641575. Epub 2018 May 23.

  PMID: 29791956 BACKGROUND

• Martinoli C, Perez MM, Padua L, Valle M, Capaccio E, Altafini L, Michaud J, Tagliafico A. Muscle variants of the upper and lower limb (with anatomical correlation). Semin Musculoskelet Radiol. 2010 Jun;14(2):106-21. doi: 10.1055/s-0030-1253155. Epub 2010 May 18.

  PMID: 20486022 BACKGROUND

• Eric M, Koprivcic I, Vucinic N, Radic R, Krivokuca D, Leksan I, Selthofer R. Prevalence of the palmaris longus in relation to the hand dominance. Surg Radiol Anat. 2011 Aug;33(6):481-4. doi: 10.1007/s00276-010-0751-0. Epub 2010 Nov 24.

  PMID: 21107568 BACKGROUND

• Dabrowski K, Stankiewicz-Jozwicka H, Kowalczyk A, Markuszewski M, Ciszek B. Musculus Palmaris Longus: Influence on Playing Capability of Keyboard Musicians - Preliminary Report. Front Psychol. 2018 Aug 13;9:1460. doi: 10.3389/fpsyg.2018.01460. eCollection 2018.

  PMID: 30150961 BACKGROUND

• Vucinic N, Eric M, Savic M. How often absence of palmaris longus and functional deficiencyof flexor digitorum superficialis occurs ? Acta Orthop Belg. 2016 Aug;82(2):405-411.

  PMID: 27682306 BACKGROUND

• Amaral JF, Mancini M, Novo Junior JM. Comparison of three hand dynamometers in relation to the accuracy and precision of the measurements. Rev Bras Fisioter. 2012 Jun;16(3):216-24. doi: 10.1590/s1413-35552012000300007.

  PMID: 22801514 BACKGROUND

• Chamorro C, Armijo-Olivo S, De la Fuente C, Fuentes J, Javier Chirosa L. Absolute Reliability and Concurrent Validity of Hand Held Dynamometry and Isokinetic Dynamometry in the Hip, Knee and Ankle Joint: Systematic Review and Meta-analysis. Open Med (Wars). 2017 Oct 17;12:359-375. doi: 10.1515/med-2017-0052. eCollection 2017.

  PMID: 29071305 BACKGROUND

• Pua YH, Wrigley TV, Cowan SM, Bennell KL. Intrarater test-retest reliability of hip range of motion and hip muscle strength measurements in persons with hip osteoarthritis. Arch Phys Med Rehabil. 2008 Jun;89(6):1146-54. doi: 10.1016/j.apmr.2007.10.028.

  PMID: 18503813 BACKGROUND

• Arnold CM, Warkentin KD, Chilibeck PD, Magnus CR. The reliability and validity of handheld dynamometry for the measurement of lower-extremity muscle strength in older adults. J Strength Cond Res. 2010 Mar;24(3):815-24. doi: 10.1519/JSC.0b013e3181aa36b8.

  PMID: 19661831 BACKGROUND

MeSH Terms

Conditions

Congenital Abnormalities; Wounds and Injuries

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Alvaro Garcia-Luna, MSc

  University of Alcala

  PRINCIPAL INVESTIGATOR

• Jose-Jesus Jimenez-Rejano, PhD

  University of Seville

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Alvaro Garcia-Luna, MSc

CONTACT

+34646777034; alvaro.garci@edu.uah.es

Jose-Jesus Jimenez-Rejano, PhD

CONTACT

+34667309369; jjjimenez@us.es

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: June 3, 2024
• First Posted: June 7, 2024
• Study Start: September 1, 2024
• Primary Completion: December 31, 2024
• Study Completion: January 31, 2025
• Last Updated: June 7, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)