NCT06572007

Brief Summary

This study aimed to investigate the impact of lumbar perimuscular and subcutaneous zone thickness on pain, functionality, disability, and depression in individuals with chronic low back pain (CLBP).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2024

Shorter than P25 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 20, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 26, 2024

Completed
20 days until next milestone

Study Start

First participant enrolled

September 15, 2024

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 25, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 25, 2024

Completed
Last Updated

October 29, 2024

Status Verified

October 1, 2024

Enrollment Period

1 month

First QC Date

August 20, 2024

Last Update Submit

October 26, 2024

Conditions

Outcome Measures

Primary Outcomes (3)

  • Visual Analog Scale (VAS)

    The Visual Analog Scale, a 100 mm long scale marked at every 10 mm and ranging from 0 to 10, will be used to assess the level of pain. Patients mark their own pain level on this scale, scoring between 0 and 10, where 0 indicates "no pain" and 10 represents "the worst possible pain"

    baseline

  • Straight Leg Raise Test (SLR)

    The Straight Leg Raise Test is a physiotherapy method used to determine the range of motion of the hip joint. The patient lies supine. They are instructed to lift one leg as high as possible without bending the knee. The leg that remains on the ground should not lift, and its knee should remain extended. The point reached by the raised leg is measured with a goniometer. The same procedure is repeated for the other leg . Normally, the hip flexion angle is 90 degrees; a range of 70-90 degrees is considered normal in adults. An angle below 70 degrees indicates restriction.

    baseline

  • Lumbar Extensor Shortening Assessment

    This physiotherapy method is used to evaluate the shortening of the extensor muscles in the lumbar region. The patient lies supine with their arms in a reverse 'T' position. They are instructed to flex both hips and knees and draw them towards their abdomen. The distance between the knees and the chest is recorded

    baseline

Secondary Outcomes (2)

  • Roland Morris Disability Questionnaire (RMDQ)

    baseline

  • Beck Depression Inventory

    baseline

Study Arms (1)

Low back pain

Fascia thickness of individuals with chronic low back pain will be measured by ultrasound and the relationship with pain, flexibility, disability and depression will be analysed.

Diagnostic Test: Ultrasound

Interventions

UltrasoundDIAGNOSTIC_TEST

To investigate the thickness of the fascia tissue, the subjects will undergo an ultrasound examination using a clinical ultrasound system (S9, SonoScape Corporation, made in China) with a linear 5-14 MHz array of L14-5/38. The transducer with a cross-section of 6.24 cm2 will be aimed at points 2 cm lateral to the midline of the L2 and L3 vertebrae on both sides of the spine.

Low back pain

Eligibility Criteria

Age30 Years - 50 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Getting a diagnosis of low back pain

You may qualify if:

  • The absence of LBP in the last 12 months,
  • A body mass index (BMI) of 18.5 to 30,
  • An age between 30 and 50 years.

You may not qualify if:

  • History of musculoskeletal diseases,
  • a history of back and lower limb surgery,
  • the use of anti-inflammatory drugs and steroids

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Emine Atıcı

Tuzla, Istanbul, Turkey (Türkiye)

Location

Istanbul Okan University

Istanbul, 34959, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Low Back PainChronic Pain

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Diagnostic ImagingDiagnostic Techniques and ProceduresDiagnosis

Study Officials

  • Emine Atıcı

    Okan University

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Target Duration
3 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 20, 2024

First Posted

August 26, 2024

Study Start

September 15, 2024

Primary Completion

October 25, 2024

Study Completion

October 25, 2024

Last Updated

October 29, 2024

Record last verified: 2024-10

Locations