Effects of Mulligan Mobilization With Movement as Compared to Kaltenborn Joint Mobilization in the Management of Knee Osteoarthritis

NCT06444945 | Enrolling By Invitation

• 1 other identifier: FUI/CTR/2024/13
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a randomised controlled trial and the purpose of this study is to determine the Effects of Mulligan mobilization with movement as compared to Kaltenborn joint mobilization in the management of knee osteoarthritis." To determine the effects of Mulligan MWM as compared to Kaltenborn joint mobilization in terms of pain, function, range of motion and gait in persons with knee osteoarthritis.

Conditions

Knee Osteoarthritis

Outcome Measures

Primary Outcomes (8)

• knee pain

  knee pain will be measured using visual analogue scale (VAS) from 0-100mm.A higher score on VAS indicated greater pain.

  2 weeks

• Functional disability

  knee functional disability will be assessed using Knee Osteoarthritis and Outcome Score(KOOS) with a score ranging from 0-100. A lower score on KOOS signifies greater functional disability

  2 weeks

• Knee range of motion

  knee range of motion will be measured using a goniometer. A higher ROM signifies positive outcome.

  2 weeks

• Stride length

  Gait analysis will be done to analyze stride length. A greater stride length signifies positive outcome and prognosis.

  2 weeks

• Gait velocity

  Gait analysis will be done to analyze gait velocity. A greater gait velocity signifies positive outcome and prognosis.

  2 weeks

• Isometeric Muscle Strength

  Isometeric Muscle Strength will be quantified using dynamometer. A higher score on dynamometer signifies greater muscle strength and good prognosis.

  2 weeks

• Walking related performance fatigability

  walking related performance fatigability will be measured using 6 minute walk test. Greater fatigibility indicates poorer outcome.

  2 weeks

• Functional Capacity

  5 repetition sit to stand test will be used to determine knee related functional capacity which will be quantified in terms of time. A smaller time will denote greater functional capacity.

  2 weeks

Study Arms (2)

Mulligan MWM group

EXPERIMENTAL

Group A receiving Mulligan MWM joint mobilization

Device: Heating pad; Device: Transcutaneous electrical nerve stimulation(TENS); Procedure: Mulligan mobilization with movement (MWM); Procedure: Resistance Training exercise

Kaltenborn mobilization group

EXPERIMENTAL

Group B receiving Kaltenborn Joint mobilization

Device: Heating pad; Device: Transcutaneous electrical nerve stimulation(TENS); Procedure: Kaltenborn joint mobilization; Procedure: Resistance Training exercise

Interventions

Heating pad DEVICE

Heating pad will be used for heating purpose.

Kaltenborn mobilization group; Mulligan MWM group

Transcutaneous electrical nerve stimulation(TENS) DEVICE

TENS is used for symptomatic pain relief

Kaltenborn mobilization group; Mulligan MWM group

Mulligan mobilization with movement (MWM) PROCEDURE

It provides short term pain relief and to restore pain-free, functional movements by achieving full range at the joint

Mulligan MWM group

Kaltenborn joint mobilization PROCEDURE

The purpose of joint mobilization is to restore normal, painless joint function. In restricted joints, this involves the restoration of joint play to normalize the roll-gliding that is essential to active movement.

Kaltenborn mobilization group

Resistance Training exercise PROCEDURE

Resistance training increases muscle strength by making your muscles work against a weight or force.

Kaltenborn mobilization group; Mulligan MWM group

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals aged 40-70 years (Osama et al, 2022)
• Having KOA history of no less than 3 months
• Knee pain less than 8/10 on numeric pain rating scale (NPRS).
• Radiological evidence of grade III or less on Kellgren classification
• Patients referred from rehab department

You may not qualify if:

• Those with signs of serious pathology, such as malignancy, inflammatory disorder or infection.
• History of trauma or fractures in lower extremity.
• Signs of lumbar radiculopathy or myelopathy.
• History of knee surgery or replacement.
• Receiving intra-articular steroid therapy in the preceding two months.

Sponsors & Collaborators

• Foundation University Islamabad: lead

Study Sites (1)

Foundation University Islamabad

Islamabad, Pakistan

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Transcutaneous Electric Nerve Stimulation; Movement; Resistance Training

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Electric Stimulation Therapy; Therapeutics; Physical Therapy Modalities; Rehabilitation; Analgesia; Anesthesia and Analgesia; Physiological Phenomena; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise Therapy; Aftercare; Continuity of Patient Care; Patient Care; Physical Conditioning, Human; Exercise; Motor Activity

Study Officials

• Shanza Fatima, DPT

  Foundation University Islamabad

  PRINCIPAL INVESTIGATOR

• Muhammad Osama, PHD*

  Foundation University Islamabad

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Parallel designed randomized control trial

Study Record Dates

• First Submitted: May 27, 2024
• First Posted: June 6, 2024
• Study Start: June 10, 2024
• Primary Completion: December 10, 2024
• Study Completion: December 30, 2024
• Last Updated: June 6, 2024

Record last verified: 2024-06

Locations

PA (1)