Colorectal Cancer Screening in Alaska Native Men

NCT06436300 | Completed Results

• 1 other identifier: R21NR019362
• Study Type: interventional
• Target: 998
• Locations: 1 country
• Sites: 1

Brief Summary

Alaska Native men have the highest rates of colorectal cancer incidence and mortality in the US. Screening can prevent disease and improve survival. A previous study tested text messages to increase colorectal cancer screening in Alaska Native patients of the Southcentral Foundation healthcare system in Anchorage, Alaska. The intervention improved screening by 50% in women, but it had no effect in men. The current study aimed to culturally tailor the intervention for Alaska Native Men, and to test it with a randomized controlled trial among patients at the Southcentral Foundation.

Conditions

Colorectal Cancer

Keywords

screening

Outcome Measures

Primary Outcomes (2)

• Number of Participants Who Completed Colorectal Cancer Screening

  Screening procedure documented in the electronic medical record

  Six months

• Number of Participants Who Scheduled a Screening-related Visit

  Pre-screening or screening visit scheduled in the electronic medical record during follow-up

  Six months

Study Arms (4)

Control

NO INTERVENTION

Usual care arm receives established methods for scheduling colorectal cancer screening with clinic patients.

Messages only

EXPERIMENTAL

Receives motivational messages to promote colorectal cancer screening plus usual care.

Behavioral: Motivational text messaging

Messages plus gift card

EXPERIMENTAL

Receives motivational messages to promote colorectal cancer screening, plus offer of a $50 gift card for completing screening, plus usual care.

Behavioral: Motivational text messaging

Messages plus raffle

EXPERIMENTAL

Receives motivational messages to promote colorectal cancer screening, plus offer of entry into a raffle for a prize worth approximately $200 if they complete screening, plus usual care.

Behavioral: Motivational text messaging

Interventions

Motivational text messaging BEHAVIORAL

Intervention sends up to 4 motivational messages by text or email to Alaska Native men who are active patients and due for colorectal cancer screening. Incentive arms include promise of a $50 gift card or entry into a raffle for prize worth about $200 if they complete screening.

Messages only; Messages plus gift card; Messages plus raffle

Eligibility Criteria

• Age: 40 Years - 75 Years
• Gender Eligibility Details: Eligibility determined in the electronic medical record, which reflects gender identity.
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Alaska Native or American Indian racial identity
• Male gender identity
• Active patient of the Southcentral Foundation in Anchorage, Alaska
• Empanelled to primary care provider in the Anchorage or local Valley area
• Eligible for routine preventive colorectal cancer screening

You may not qualify if:

• None

Sponsors & Collaborators

• Washington State University: lead
• Southcentral Foundation: collaborator

Study Sites (1)

Southcentral Foundation

Anchorage, Alaska, 99508, United States

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Limitations and Caveats

This study was limited to male patients at a single Tribal health care system in the Anchorage Metropolitan Area. Results may not generalize to other Alaska Native or American Indian people in other locations or settings. Colorectal cancer screening performed outside of the health care system would not be included in outcome data, but the vast majority of patients receive most or all their care from the Southcentral Foundation and we anticipate minimial misclassification of screening.

Results Point of Contact

• Title: Clemma Muller
• Organization: Washington State University

clemma.muller@wsu.edu

612-327-7237

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: Parallel arm randomized controlled trial

Study Record Dates

• First Submitted: May 24, 2024
• First Posted: May 31, 2024
• Study Start: August 1, 2023
• Primary Completion: January 31, 2024
• Study Completion: January 31, 2024
• Last Updated: August 29, 2025
• Results First Posted: August 29, 2025

Record last verified: 2025-08

Locations

US (1)