Colorectal Cancer Screening Intervention Study

NCT06424197 | Completed DMC

• 2 other identifiers: IRB-FY2023-3R21MD016506
• Study Type: interventional
• Target: 799
• Locations: 1 country
• Sites: 1

Brief Summary

Colorectal cancer (CRC) is one of the leading causes of cancer mortality in the United States, and African Americans (AfAms) still fare worse in CRC incidence and mortality compared to European Americans (EuAms). We propose to examine whether combining both fear-reduction and racially-targeted norm-based messages will increase at-home stool-based CRC screening receptivity and uptake for all African American regardless of level of racial identity. Given low return rates of at-home screening kits, we will also explore whether making an explicit commitment to return screening kits is associated with increased kit returns.

Conditions

Colorectal Cancer

Keywords

Colorectcal Cancer Screening Targeted Message Intervention

Outcome Measures

Primary Outcomes (1)

• FIT Kit request

  FIT Kit request

  Immediately after survey

Secondary Outcomes (1)

• FIT Kit return

  3 months

Study Arms (4)

Norm Based Messages

EXPERIMENTAL

One of 3 messaging entreaties based on normative perceptions of colorectal cancer screening, and one no norm-based messaging arm.

Other: Racial group-targeted messages

Fear Reduction Message

EXPERIMENTAL

Participants randomized to receive (or not receive) messaging entreaty to address colorectal cancer screening fears.

Other: Racial group-targeted messages

Commitment

EXPERIMENTAL

Participants randomized to indicate explicit commitment to return FIT Kits for processing.

Other: Explicit Commitment

Control

NO INTERVENTION

Participants receive no health messages.

Interventions

Racial group-targeted messages OTHER

Colorectal cancer screening messages targeted towards participants racial group.

Fear Reduction Message; Norm Based Messages

Explicit Commitment OTHER

Indicate explicit commitment to return at home screening kit.

Commitment

Eligibility Criteria

• Age: 45 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• African American Overdue to colorectal cancer screening Has primary care physician Not at high risk for colorectal cancer

Sponsors & Collaborators

• Oakland University: lead
• National Institutes of Health (NIH): collaborator
• National Institute on Minority Health and Health Disparities (NIMHD): collaborator

Study Sites (1)

Oakland University

Rochester, Michigan, 48309, United States

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Officials

• Mark Manning, PhD

  Oakland University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SCREENING
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 16, 2024
• First Posted: May 22, 2024
• Study Start: March 1, 2023
• Primary Completion: April 23, 2024
• Study Completion: August 31, 2024
• Last Updated: August 8, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)