Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community

NCT06413030 | Enrolling By Invitation DMC

• 1 other identifier: CEC_FP_2023023
• Study Type: observational
• Target: 383
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to evaluate the relationship of gait speed with dynapenic or sarcopenic obesity in community-dwelling older people. The main questions it aims to answer are:

• Is slow walking speed related to overweight in older people in the community?
• Is slow walking speed related to dynapenic obesity in older people in the community?
• Is gait speed related to sarcopenic obesity in older people in the community? Participants will answer a clinical interview to obtain sociodemographic data and will perform the following clinical tests: (1) 10-meter walk test, (2) Anthropometric measurement; (3) Handgrip dynamometry test, (4) Standing dynamometry test and (5) Physical functionality questionnaires.

Conditions

Frailty; Obesity; Sarcopenia; Sarcopenic Obesity; Gait Speed

Keywords

aged; Aged, 80 and over

Outcome Measures

Primary Outcomes (3)

• Gait Speed

  A well-lit, unobstructed flat corridor with an extension of 10 meters is used for the test. Ground markings are added at 0 and 10 meters apart, with 2 meters start (acceleration) and 2 meters end (deceleration) added to allow participants room to accelerate and decelerate their walk outside the data collection area to help reduce the gait variability introduced during these phases. Subjects were instructed to walk at a usual and comfortable speed, without running or stopping. Subjects are allowed to use usual technical aids for walking, including walkers or canes if required. Chronometers based on smartphones to time the route between the second and third line of the route that consists of the 10 timed meters. The stopwatch records the time at which the subject's toe crossed the line. This sequence is repeated three times with 1 minute rest periods. The average of the three trials is used to determine the walking speed.

  Month 1

• Anthropometric measures

  Biospace Inbody: Individuals are placed in a standing position with 30º flexion of the scapulo-humeral joint. 8 electrodes are used located on: feet (metatarso-calcaneus) and hands (metacarpals 2nd-5th finger and phalanx of the thumb). The induction frequency is assessed with 6 different intensities (1, 5, 50, 250, 500 kHz and 1 MHz), with a fat mass estimation sensitivity of 0.1 kg (0.1%). From this measurement we obtain: percentage of muscle mass, percentage of general fat, percentage of visceral fat and bone weight.

  Month 1

• Handgrip dynamometry

  To evaluate manual muscle strength, the Baseline handgrip dynamometer will be used. The assessment is carried out with the subject in a seated position in a chair without armrests, with the back and feet adequately supported on the floor while the hips and knees are at 90°. The position was with shoulders adducted and neutrally rotated, elbows flexed at 90° and forearms in a neutral position. We began by evaluating the dominant hand by positioning the wrist between 15 and 30° of extension and between 0° and 15° of ulnar deviation. The dynamometer must be used in a vertical position, and parallel to the forearm, while the participant grips the handle with a thumbs up. 3 repetitions were performed for each limb, obtaining an average of the measurements, the grip time will be 3 to 6 seconds with a rest time of 1 minute, using the best value for data analysis.

  Month 1

Study Arms (1)

Community-dwelling older adults

Persons over 60 years of age attending primary health care centers in the Bio Bio Region of Chile.

Diagnostic Test: 10 Meter Walk Test

Interventions

10 Meter Walk Test DIAGNOSTIC_TEST

Gait Speed Test

Community-dwelling older adults

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Older people who live in the community and attend primary health care centers in the Bio Bio Region of Chile.

You may qualify if:

• Subjects over 60 years of age
• Female and male
• Self-sufficient in the instrumental activities of daily living
• Subjects with or without drug consumption, capable of carrying out the activity of walking independently or dependent on technical aids.

You may not qualify if:

• Subjects with acute musculoskeletal injuries of the lower extremity.

Sponsors & Collaborators

• University of Americas: lead

Study Sites (1)

Universidad de las Américas

Concepción, Chile

Location

MeSH Terms

Conditions

Frailty; Obesity; Sarcopenia

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical

Study Officials

• Karen Córdova-León, PT

  Academic

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Academic Leader

Study Record Dates

• First Submitted: May 6, 2024
• First Posted: May 14, 2024
• Study Start: February 1, 2024
• Primary Completion: September 30, 2024
• Study Completion: December 31, 2024
• Last Updated: May 14, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR

Locations

CL (1)