Prognostic Role of LA Strain in Acute Myocardial Infarction

NCT06408636 | Completed

• 1 other identifier: XYFY2023-KL222-01
• Study Type: observational
• Target: 780
• Locations: 1 country
• Sites: 1

Brief Summary

This is a single-center retrospective observational study in which we consecutively selected patients diagnosed with acute myocardial infarction from September 2019 to March 2024 at the Affiliated Hospital of Xuzhou Medical University. Inclusion criteria: 1. CMR was completed during all hospitalizations; 2. complete clinical data; 3. received continuous cardiac monitoring during hospitalization. Exclusion criteria: 1. unclear or non-compliant CMR images; 2. previous history of myocardial infarction; 3. malignant tumors diseases. Dedicated cardiovascular imaging software CVI42 (cvi42® version 5.13.5, Circle Cardiovascular Imaging, Canada) was used for image analysis. LA strain was obtained by cardiac MRI feature tracking. Patient prognosis was obtained through chart notes and telephone follow-up. Major events included atrial fibrillation, ischemic stroke, and all-cause mortality.

Conditions

Atrial Fibrillation; Myocardial Infarction, Acute; Stroke Ischemic; Mortality

Keywords

cardiac magnetic resonance; myocardial infarction; atrial fibrillation; ischemic stroke

Outcome Measures

Primary Outcomes (1)

• Primary endpoint events included all-cause death, ischemic stroke, and atrial fibrillation

  All patients were followed until March 31, 2024

Study Arms (1)

We consecutively selected patients diagnosed with acute myocardial infarction from September 2019 th

Other: Cardiac MRI

Interventions

Cardiac MRI OTHER

All selected patients completed a cardiac magnetic resonance examination without other interventions.

We consecutively selected patients diagnosed with acute myocardial infarction from September 2019 th

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This is a single-center retrospective observational study in which we consecutively selected patients diagnosed with acute myocardial infarction from September 2019 to March 2024 at the Affiliated Hospital of Xuzhou Medical University. Dedicated cardiovascular imaging software CVI42 (cvi42® version 5.13.5, Circle Cardiovascular Imaging, Canada) was used for image analysis. LA strain was obtained by cardiac MRI feature tracking. Patient prognosis was obtained through chart notes and telephone follow-up. Major events included atrial fibrillation, ischemic stroke, and all-cause mortality.

You may qualify if:

• CMR was completed during all hospitalizations; 2. complete clinical data; 3. received continuous cardiac monitoring during hospitalization.

You may not qualify if:

• unclear or non-compliant CMR images; 2. previous history of myocardial infarction; 3. malignant tumors diseases.

Sponsors & Collaborators

• The Affiliated Hospital of Xuzhou Medical University: lead

Study Sites (1)

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, 221002, China

Location

MeSH Terms

Conditions

Atrial Fibrillation; Myocardial Infarction; Ischemic Stroke

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Myocardial Ischemia; Vascular Diseases; Infarction; Ischemia; Necrosis; Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 7, 2024
• First Posted: May 10, 2024
• Study Start: September 2, 2019
• Primary Completion: March 31, 2024
• Study Completion: March 31, 2024
• Last Updated: May 10, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)