The Impact of Laparotomy and Analgesia Methods on Diaphragm
1 other identifier
observational
90
1 country
1
Brief Summary
Major abdominal surgeries are traditionally performed via laparotomy. Analgesia is routinely administered during the postoperative period. The goal is to investigate the effects of laparotomy and analgesia methods on diaphragm function.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2025
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 3, 2024
CompletedFirst Posted
Study publicly available on registry
May 8, 2024
CompletedStudy Start
First participant enrolled
January 30, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2025
CompletedApril 30, 2025
April 1, 2025
5 months
May 3, 2024
April 29, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
The impact of laparotomy on diaphragm thickness.
Comparison of diaphragm muscle measurements before and after surgery
Measurement at the 1st postoperative hour
Secondary Outcomes (1)
The effect of analgesia methods on diaphragm thickness in patients undergoing laparoscopic surgery.
Measurement at the 1st postoperative hour
Study Arms (1)
diaphragm contraction fraction
Diaphragm muscle contraction fraction measured before and after surgery
Interventions
Using ultrasonography to measure diaphragm thickness
Eligibility Criteria
Patients scheduled for major abdominal surgery due to gastrointestinal tumor
You may qualify if:
- over 18 years,
- major abdominal surgery cases
You may not qualify if:
- body mass index (BMI) \>35 kg/m2
- illiteracy,
- communication issues,
- neuromuscular disorders,
- Advanced chronic respiratory disease,
- Previous abdominal or thoracic surgery
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Prof. Dr. Cemil Taşcıoğlu City Hospital
Istanbul, Turkey (Türkiye)
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
May 3, 2024
First Posted
May 8, 2024
Study Start
January 30, 2025
Primary Completion
July 1, 2025
Study Completion
August 1, 2025
Last Updated
April 30, 2025
Record last verified: 2025-04