Key Insights

Highlights

Success Rate

83% trial completion

Published Results

80 trials with published results (12%)

Research Maturity

303 completed trials (47% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

9.7%

63 terminated out of 650 trials

Success Rate

82.8%

-3.8% vs benchmark

Late-Stage Pipeline

10%

66 trials in Phase 3/4

Results Transparency

26%

80 of 303 completed with results

Key Signals

80 with results83% success63 terminated

Data Visualizations

Phase Distribution

500Total
Not Applicable (211)
Early P 1 (3)
P 1 (87)
P 2 (133)
P 3 (50)
P 4 (16)

Trial Status

Completed303
Unknown136
Recruiting73
Terminated63
Not Yet Recruiting37
Active Not Recruiting22

Trial Success Rate

82.8%

Benchmark: 86.5%

Based on 303 completed trials

Clinical Trials (650)

Showing 20 of 20 trials
NCT06750094Phase 3RecruitingPrimary

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

NCT07740122RecruitingPrimary

AI-Based Stool Image Analysis for Colorectal Neoplasia Risk Assessment

NCT07715903Phase 1Not Yet RecruitingPrimary

Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy

NCT06662786Phase 3RecruitingPrimary

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

NCT07071454Not ApplicableNot Yet RecruitingPrimary

Preventing Early-Onset Colorectal Cancer in the VA

NCT04222413Phase 1Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

NCT01915225RecruitingPrimary

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

NCT07222800Phase 3Recruiting

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

NCT03485209Phase 2Active Not RecruitingPrimary

Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

NCT05253651Phase 3RecruitingPrimary

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

NCT06131840Phase 1RecruitingPrimary

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

NCT06447662Phase 1Active Not Recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

NCT07114601Phase 1Recruiting

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT02484404Phase 1Active Not RecruitingPrimary

Phase I/II Study of the Anti-Programmed Death Ligand-1 Durvalumab Antibody (MEDI4736) in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Can...

NCT07705880RecruitingPrimary

A Novel Clinical Decision Support Tool to Predict Submucosal Invasive Cancer Within Large Non-Pedunculated Colorectal Polyps

NCT05612347Not ApplicableRecruiting

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

NCT05451849Phase 1Terminated

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

NCT05286814Phase 2Recruiting

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

NCT06411756Not ApplicableCompletedPrimary

Physical Activity Centers Empowerment

NCT07213791Phase 1Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

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Research Network

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